This volume discusses that latest cell therapy methods for neurological diseases using bone marrow-derived mononuclear cells, mesenchymal stem cells, dental pulp stem cells, adipose-derived stem cells, cord blood cells, and amnion cells. The chapters in this book also cover specific diseases such as cerebral infarction, spinal cord injury, amyotrophic lateral sclerosis, neuropathic pain, and hypoxic-ischemic encephalopathy. Each chapter includes a detailed description of the protocol for preparing the cells used, the method for producing the animals used, and the characteristics of patients with each disease, as well as an explanation of the behavioral experiments, molecular biochemical experiments, and other methods required to evaluate the effectiveness of the treatment. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and practical, Regenerative Cellular Therapies for Neurological Diseases is a valuable resource for graduate students and postdoctoral researchers who want to learn more about this field and develop cell therapies for neurological diseases.

Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts

Inhalt

Bone Marrow-Derived Mononuclear Cells for Stroke.- Autologous Mesenchymal Stem Cells Derived from Adipose Tissue for Acute Spinal Cord Injury.- Bone Marrow-Derived Mononuclear Cells for Spinal Cord Injury.- Bone Marrow-Derived Inducible Microglia-Like (BM-iMG) Cells for Amyotrophic Lateral Sclerosis.- Adipose-Derived Stem Cells for Amyotrophic Lateral Sclerosis.- Bone Marrow-Derived Cells with GLT1 Gene Delivery for Amyotrophic Lateral Sclerosis.- Combination Therapy of Bone Marrow-Derived Mononuclear Cells and Mesenchymal Stem Cells Expressing Growth Factors for Amyotrophic Lateral Sclerosis.- Differentiation of Human Dental Pulp Stem Cells (hDPSCs) into GABAergic Neuron-Like Cells for Personalized Cell Therapy.- Bone Marrow-Derived Mononuclear Cells for Neuropathic Pain.- Bone Marrow-Derived Mesenchymal Stromal Cells for Neonatal Hypoxic-Ischemic Encephalopathy in Mice.- Transplantation of Human Cord Blood.- Model of Neonatal Ischemia-Reperfusion Brain Injury.- Human Amnion-Derived Cells for Neonatal Hypoxic-Ischemic Encephalopathy in Mice.