The book Topical Products and Dermal Drug Delivery delves deeply into critical topics essential for professionals across industry, academia, and clinical research. Inspired by a decade of groundbreaking global research, much of which has received USFDA funding, this comprehensive work offers readers valuable insights with a regulatory lens woven into many chapters. Notably, the book provides a pioneering depth of coverage on certain subjects. A unique perspective has been provided by the authors regarding topics such as metamorphosis, in vitro permeation testing, sublimation of APIs, quality attributes of topical products, microscopic techniques and MuST studies.

This book offers an exceptional view on the development, characterization and performance evaluation of topical products Combines regulatory framework with scientific rationale, offering innovative insights for assessing product quality Authored by experts with USFDA collaboration, this authoritative resource is practical for professionals in the field

Autorentext

S. Narasimha Murthy is Chief Scientific Officer of Topical Products Testing LLC in Oxford, Massachusetts.

Inhalt

Chapter 1 Dermal drug delivery formulations and critical quality attributes.- Chapter 2 Evaporative metamorphosis in topical products.- Chapter 3 Classification of Topical Products.- Chapter 4 Sensorial Characterization and their impact on the treatment outcome.- Chapter 5 Lipid based drug delivery systems in topical delivery.- Chapter 6 Approaches to minimize the dermal absorption of drugs intended for locoregional activity.- Chapter 7 Regional molecular targets in the skin for treating cutaneous and neurological disorders.- Chapter 8 Repurposing of systemically administered drugs for topical treatments.- Chapter 9 In vitro permeation testing, an art and science of testing the topical products.- Chapter 10 Regulatory pathway of approval of dermatological products.- Chapter 11 Future technologies for delivery and sampling of drugs form the skin.- Chapter 12 Novel techniques of investigating dermatokinetics of drugs.- Chapter 13 Forced perfusion microdialyais technique.- Chapter 14 Emerging technologies in transdermal drug delivery.