Essential Pharmaceutics

Particularly in healthcare fields, there is a growing movement away from traditional lecture style courses towards active learning and team-based activities to improve retention of concepts and build higher level thinking through the application of complex problems with a strong foundation of facts and data. Essential Pharmaceutics is suited to this modern teaching style and is the first book of its kind of provide the resources and skills needed for the successful implementation of an active learning basic pharmaceutics course. This text offers a format that is specifically suited for integration in an active learning, team-based classroom setting. It is ideal for self-learning for the beginning pharmaceutics student, based upon the extensive utilization of figures, tables, and its overview of essential topics in pharmaceutics. Essential Pharmaceutics provides the requisite foundational knowledge for the development and implementation of case studies based upon modern drug products.

Extensive utilization of figures schematics and tables makes it ideal for self-learning Designed to provide foundational knowledge for utilization of modern drug products in flipped classroom Second edition is updated using the knowledge from the author's personal experience teaching in the flipped classroom

Autorentext

Ashlee D. Brunaugh is an Assistant Professor at the University of Michigan College of Pharmacy in the Department of Pharmaceutical Sciences. She is also the President/CEO of CloXero Therapeutics Inc and a Scientific Advisor for Via Therapeutics LLC. Dr. Brunaugh holds both a Pharm.D. and a Ph.D degree in Pharmaceutical Sciences from the University of Texas at Austin. Upon completing her education, she worked as a Senior Scientist and later Director of Strategy and Operations at Via Therapeutics, a pharmaceutical start-up located in Austin TX focused on the bridging of novel drug delivery systems from the pre-clinical to clinical stages of development. In 2021, she joined the faculty at the University of Michigan. Dr. Brunaugh's research is focused on the elucidation of the underlying mechanisms for respiratory disease progression to determine appropriate therapeutic targets and develop novel formulation and drug delivery approaches to improve patient outcomes. In addition to her research experience, Dr. Brunaugh is a registered pharmacist and has experience practicing in hospital, community and clinical trial settings. She has several years of experience in teaching pharmaceutical science courses at the undergraduate and graduate level, including the development and implementation of a flipped-classroom basic pharmaceutics course with Drs. Smyth and Williams at the University of Texas at Austin College of Pharmacy. Daniel Moraga-Espinoza is a Pharmacist from Universidad de Valparaíso, Chile (2010), and completed a Ph.D. in Molecular Pharmaceutics and Drug Delivery (MPDD) at the University of Texas at Austin, U.S. (2018). Presently, Dr. Moraga-Espinoza holds the position of Assistant Professor at Universidad de Valparaíso, serves as an adjunct professor at the University of Texas at Austin, and works as an associate researcher at the Chilean Pharmacopeia Research Center. His primary research focus lies in the field of drugdelivery into the lungs and the nasal cavity through controlled release systems. He has published multiple research articles, reviews, book chapters, and patent applications. Additionally, he is member of the editorial boards of the scientific journals Drug Development and Industrial Pharmacy (DDIP) (2018) and AAPS PharmSciTech journal (2018). Dr. Moraga was the recipient of the Grant FONDECYT de iniciación 11190987 for young researchers, honored as one of the leading research innovators by BRAIN Chile (2023), and serves as a regulatory consultant for the Chilean regulatory agency, contributing to the development of guidelines for the evaluation of orally and nasally inhaled drug products. Tania F. Bahamondez-Canas is a Pharmacist from Universidad de Valparaiso, Chile (2010), and a Ph.D. from the University of Texas at Austin, US (2018). She is an Associate Professor at Universidad de Valparaiso, Chile, an academic position sponsored by the Chilean Agency of Research and Development (ANID) with the grant PAI 77190010 (2019). She is also an Adjunct Professor of the Ph.D. program in Molecular Pharmaceutics and Drug Delivery at the University of Texas at Austin, US. She has teaching experience in various programs from the College of Pharmacy of Universidad de Valparaíso, including undergraduate pharmacy, master's, and continuing education programs. She is the director of the Chilean Pharmacopeia Research Center (CIFAR) at Universidad de Valparaíso and PI of the Antimicrobial Pharmaceutics laboratory focusing on novel drug delivery systems to effectively fight bacterial biofilm infections. She has published multiple research articles, reviews, book chapters, and patent applications. Her work on biofilm infections and tissue engineering in chronic wounds has been funded by the ANID grants for young researchers FONDECYT 11190348 (2019) and applied sciences FONDEF ID19I10028 (2019) and FONDEF ID21I10153 (2021), and recently awarded by the Chilean regulatory agency (ISP).

Inhalt
Chapter 1: Essential Pharmaceutics in the Flipped-Classroom. - Chapter 2: Overview of Biopharmaceutics and Regulatory Concepts Relevant to Drug Product Design.- Chapter 3: Preformulation in Drug Product Design.- Chapter 4: Capsule and Tablet Dosage Forms.- Chapter 5: Modified Release Solid Oral Dosage Forms.- Chapter 6: Solution-Based Dosage Forms and Sterile Products.- Chapter 7: Disperse Systems Suspensions.- Chapter 8: Disperse Systems Emulsions.- Chapter 9: Ophthalmic and Otic Drug Delivery.- Chapter 10: Topical and Transdermal Drug Delivery.- Chapter 11: Oral Transmucosal Delivery.- Chapter 12: Rectal and Vaginal Drug Delivery.- Chapter 13: Pulmonary Drug Delivery.- Chapter 14: Nasal Drug Delivery.- Chapter 15: Drug Product Design and Delivery of Biologics.