This book first describes medical devices in relation to regenerative medicine before turning to a more specific topic: artificial heart technologies. Not only the pump mechanisms but also the bearing, motor mechanisms, and materials are described, including expert information. Design methods are described to enhance hemocompatibility: main concerns are reduction of blood cell damage and protein break, as well as prevention of blood clotting. Regulatory science from R&D to clinical trials is also discussed to verify the safety and efficacy of the devices.

First book to address this topic from the perspective of mechanical designers for artificial hearts Explains not only the history of how to use the artificial heart, but also the detailed mechanisms of pulsatile / nonpulsatile VADs (ventricular assist devices), which may help to advance this field in the near future Describes all the production processes for VADs Includes supplementary material: sn.pub/extras

Inhalt
Introduction.- What kinds of artificial heart are available?.- How do we select pump types?.- Selection of bearing types: Key to durability.- Motor, battery, and magnetic suspension.- Flow visualization and computational fluid dynamic analysis.- How do we select materials?.- Enhancement of hemocompatibility.- System evaluation.- Remarks and future aspects.