This book first describes medical devices in relation to regenerative medicine before turning to a more specific topic: artificial heart technologies. Not only the pump mechanisms but also the bearing, motor mechanisms, and materials are described, including expert information. Design methods are described to enhance hemocompatibility: main concerns are reduction of blood cell damage and protein break, as well as prevention of blood clotting. Regulatory science from R&D to clinical trials is also discussed to verify the safety and efficacy of the devices.

Inhalt
Introduction.- What kinds of artificial heart are available?.- How do we select pump types?.- Selection of bearing types: Key to durability.- Motor, battery, and magnetic suspension.- Flow visualization and computational fluid dynamic analysis.- How do we select materials?.- Enhancement of hemocompatibility.- System evaluation.- Remarks and future aspects.