The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts in their field, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. On the cusp of a revolution, musculoskeletal repair is based on new tools that have recently become available or are about to emerge into clinical practice. By their very nature, these tools require an interdisciplinary approach, utilizing teams comprised of surgeons, engineers, and scientists in collaboration between industry and academia. A valuable resource for researchers, developers, and clinicians, this volume presents a foundation to propel the technology and integration of the current state of knowledge into the twenty-first century.

A comprehensive but succinct reference for the field of musculoskeletal tissue regeneration Chapters are organized logically to build upon concepts The pros and cons of competing or alternative technologies are presented objectively The authors conclude each chapter with an estimate of where the field is headed

Inhalt
Background.- Musculoskeletal and Wound Treatment Through the Ages: A Brief Historical Tour.- Musculoskeletal Fundamentals: Form, Function, and a Survey of Healing Strategies.- Overview of Fracture Repair.- Hard Tissue Technologies.- Autograft Bone.- Biology of Bone Allograft and Clinical Application.- Demineralized Bone Matrix: Maximizing New Bone Formation for Successful Bone Implantation.- Deproteinized Bovine Bone Xenograft.- Bioactive Bioceramics.- Distraction Osteogenesis of the Orthopedic Skeleton: Basic Principles and Clinical Applications.- Distraction Osteogenesis of the Facial Skeleton.- Bone Morphogenetic Proteins and Other Bone Growth Factors.- Biological Approaches to Spinal Fusion.- Electrical Bone Stimulation.- Soft Tissue Technologies.- Meniscus Repair Techniques.- Lessons Learned From Our First 100 Meniscus Allograft Transplants in Arthritic Knees.- Tissue Engineering of the Meniscus.- Osteochondral Grafts.- Autologous Chondrocyte Cartilage Repair.- Autograft and Allograft ACL Reconstruction: Construct Rationale.- Tissue Engineered Anterior Cruciate Ligament Graft.- Biologic Scaffold Materials for Orthopaedic Soft Tissue Reconstruction.- Muscle Repair after Injury and Disease.- Generalized Approaches.- Principles of Musculoskeletal Tissue Banking.- Bioabsorbable Polymer Applications in Musculoskeletal Fixation and Healing.- Tissue Adhesives: Science, Products, and Clinical Use.- Platelet-Rich Plasma in Orthopedics.- Gene Therapy Approaches for Musculoskeletal Tissue Regeneration.- Paradigms of Tissue Engineering with Applications to Cartilage Regeneration.- The Future.- The Future of Musculoskeletal Tissue Regeneration: A Clinical Perspective.