Medical Image Computing and Computer-Assisted Intervention - MICCAI 2000

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In previous work [6], we presented a novel information theoretic approach for calculating fMRI activation maps. The information-th...

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In previous work [6], we presented a novel information theoretic approach for calculating fMRI activation maps. The information-theoretic approach is - pealing in that it is a principled methodology requiring few assumptions about the structure of the fMRI signal. In that approach, activation was quanti?ed by measuring the mutual information (MI) between the protocol signal and the fMRI time-series at a givenvoxel.This measureis capable of detecting unknown nonlinear and higher-order statistical dependencies. Furthermore, it is relatively straightforward to implement. In practice,activation decisions at eachvoxelareindependent of neighboring voxels. Spurious responses are then removed by ad hoc techniques (e.g. morp- logicaloperators).Inthispaper,wedescribeanautomaticmaximumaposteriori (MAP) detection method where the well-known Ising model is used as a spatial prior.The Isingspatialpriordoes not assumethat the time-seriesofneighboring voxelsareindependentofeachother.Furthermore,removalofspuriousresponses is an implicit component of the detection formulation. In order to formulate the calculation of the activation map using this technique we ?rst demonstrate that the information-theoretic approach has a natural interpretation in the hypo- esis testing framework and that, speci?cally, our estimate of MI approximates the log-likelihood ratio of that hypothesis test. Consequently, the MAP det- tion problem using the Ising model can be formulated and solved exactly in polynomial time using the Ford and Fulkerson method [4]. We compare the results of our approach with and without spatial priors to an approachbased on the general linear model (GLM) popularized by Fristonet al [3]. We present results from three fMRI data sets. The data sets test motor, auditory, and visual cortex activation, respectively.
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Inhalt
Neuroimaging and Neurosurgery.- A 3-Dimensional Database of Deep Brain Functional Anatomy, and Its Application to Image-Guided Neurosurgery.- Simulation of Corticospinal Tract Displacement in Patients with Brain Tumors.- Registration of 3D Intraoperative MR Images of the Brain Using a Finite Element Biomechanical Model.- Telesurgery System for Intravascular Neurosurgery.- Automatic Recognition of Cortical Sulci Using a Congregation of Neural Networks.- BrainSuite: An Automated Cortical Surface Identification Tool.- Incorporating Spatial Priors into an Information Theoretic Approach for fMRI Data Analysis.- Small Sample Size Learning for Shape Analysis of Anatomical Structures.- Robust Midsagittal Plane Extraction from Coarse, Pathological 3D Images.- 3-D Reconstruction of Macroscopic Optical Brain Slice Images.- Ultrasound/MRI Overlay with Image Warping for Neurosurgery.- Model-Updated Image-Guided Neurosurgery: Preliminary Analysis Using Intraoperative MR.- Automatic Landmarking of Cortical Sulci.- The Skull Stripping Problem in MRI Solved by a Single 3D Watershed Transform.- A Comparative Statistical Error Analysis of Neuronavigation Systems in a Clinical Setting.- Segmentation.- Detection and Quantification of Line and Sheet Structures in 3-D Images.- Fusing Speed and Phase Information for Vascular Segmentation in Phase Contrast MR Angiograms.- Intraoperative Segmentation and Nonrigid Registration for Image Guided Therapy.- Efficient Semiautomatic Segmentation of 3D Objects in Medical Images.- Space and Time Shape Constrained Deformable Surfaces for 4D Medical Image Segmentation.- Adaptive-Focus Statistical Shape Model for Segmentation of 3D MR Structures.- Non-linear Diffusion for Interactive Multi-scale Watershed Segmentation.- Medial-Guided Fuzzy Segmentation.- Robust 3D Segmentation of Anatomical Structures with Level Sets.- A Curve Evolution Approach to Medical Image Magnification via the Mumford-Shah Functional.- Image Segmentation Based on the Integration of Markov Random Fields and Deformable Models.- Segmentation by Adaptive Geodesic Active Contours.- Interactive Organ Segmentation Using Graph Cuts.- Oncology.- Distribution of Prostate Cancer for Optimized Biopsy Protocols.- Hybrid Classification Approach of Malignant and Benign Pulmonary Nodules Based on Topological and Histogram Features.- MRI Mammography 2D/3D Data Fusion for Breast Pathology Assessment.- Pre- and Intra-operative Planning and Simulation of Percutaneous Tumor Ablation.- Volume and Shape Preservation of Enhancing Lesions when Applying Non-rigid Registration to a Time Series of Contrast Enhancing MR Breast Images.- Local Integration of Commercially Available Intra-operative MR-scanner and Neurosurgical Guidance for Metalloporphyrin-Guided Tumor Resection and Photodynamic Therapy.- Differential Geometry Based Vector Fields for Characterizing Surrounding Structures of Pulmonary Nodules.- Medical Image Analysis and Visualization.- Non-distorting Flattening for Virtual Colonoscopy.- HeartPerfect: Data Mining in a Large Database of Myocardial Perfusion Scintigraphy.- Retrospective Correction of MR Intensity Inhomogeneity by Information Minimization.- Comparison of Three High-End Endoscopic Visualization Systems on Telesurgical Performance.- Three-Dimensional Slice Image Overlay System with Accurate Depth Perception for Surgery.- Surgical Navigation System with Intuitive Three-Dimensional Display.- Functional Analysis of the Vertebral Column Based on MR and Direct Volume Rendering.- Toward a Common Validation Methodology for Segmentation and Registration Algorithms.- An Improved Metric Space for Pixel Signatures.- Registration.- Evaluation of an Automatic System for Simulator/Portal Image Matching.- Image Registration by Maximization of Combined Mutual Information and Gradient Information.- An Image Registration Approach to Automated Calibration for Freehand 3D Ultrasound.- Symmetrization of the Non-rigid Registration Problem Using Inversion-Invariant Energies: Application to Multiple Sclerosis.- Modeling and Analysis of Ultrasonic Echoes Reflected from a Surface under Two Layers.- Localization of 3D Anatomical Point Landmarks in 3D Tomographic Images Using Deformable Models.- Fiducial Registration from a Single X-Ray Image: A New Technique for Fluoroscopic Guidance and Radiotherapy.- Multimodal Non-rigid Warping for Correction of Distortions in Functional MRI.- Robust 3D Deformation Field Estimation by Template Propagation.- Tetrahedral Mesh Modeling of Density Data for Anatomical Atlases and Intensity-Based Registration.- Nonrigid Registration of 3D Scalar, Vector and Tensor Medical Data.- A Fluoroscopic X-Ray Registration Process for Three-Dimensional Surgical Navigation.- Block Matching: A General Framework to Improve Robustness of Rigid Registration of Medical Images.- Generalized Correlation Ratio for Rigid Registration of 3D Ultrasound with MR Images.- Surgical Planning and Simulation.- Simulating Minimally Invasive Neurosurgical Interventions Using an Active Manipulator.- Bayesian Estimation of Intra-operative Deformation for Image-Guided Surgery Using 3-D Ultrasound.- Modifying Soft Tissue Models: Progressive Cutting with Minimal New Element Creation.- Interaction Techniques and Vessel Analysis for Preoperative Planning in Liver Surgery.- First Steps in Eliminating the Need for Animals and Cadavers in Advanced Trauma Life Support®.- Planning and Simulation of Robotically Assisted Minimal Invasive Surgery.- A Framework for Predictive Modeling of Intra-operative Deformations: A Simulation-Based Study.- Real-Time Large Displacement Elasticity for Surgery Simulation: Non-linear Tensor-Mass Model.- Endoscopy/Laproscopy.- Multi-DOF Forceps Manipulator System for Laparoscopic Surgery.- A Wide-Angle View Endoscope System Using Wedge Prisms.- Computer-Assisted TURP Training and Monitoring.- Cardiac Image Analysis.- Estimating 3D Strain from 4D Cine-MRI and Echocardiography: In-Vivo Validation.- Automating 3D Echocardiographic Image Analysis.- MyoTrack: A 3D Deformation Field Method to Measure Cardiac Motion from Gated SPECT.- Vascular Image Analysis.- An Adaptive Minimal Path Generation Technique for Vessel Tracking in CTA/CE-MRA Volume Images.- Exploiting Weak Shape Constraints to Segment Capillary Images in Microangiopathy.- Guide Eire Tracking During Endovascular Interventions.- A Deformable Vessel Model with Single Point Initialization for Segmentation, Quantification, and Visualization of Blood Vessels in 3D MRA.- Development of a Computer Program for Volume Estimation of Arteriovenous Malformations from Biplane DSA Images.- Geometrical and Morphological Analysis of Vascular Branches from Fundus Retinal Images.- Visualization.- Computer-Based Assessment of Body Image Distortion in Anorexia Nervosa Patients.- A Realistic Model of the Inner Organs from the Visible Human Data.- Automatic Centerline Extraction for 3D Virtual Bronchoscopy.- Mixed Reality Merging of Endoscopic Images and 3-D Surfaces.- Improving Triangle Mesh Quality with SurfaceNets.- diSNei: A Collaborative Environment for Medical Images Analysis and Visualization.- Surgical Navigation.- Impact of Combined Preoperative Three-Dimensional Computed Tomography and Intraoperative Real-Time Three-Dimensional Ultrasonography on Liver Surgery.- AR Navigation System for Neurosurgery.- Magneto-Optic Hybrid 3-D Sensor for Surgical Navigation.- Computer Assisted ENT Surgery Using Augmented Reality: Preliminary Results on the CAESAR Project.- Interventions under Video-Augmented X-Ray Guidance: Application to Needle Placement.- The Varioscope AR A Head-Mounted Operating Microscope for Augmented Reality.- Medical Robotics.- An Active Hand-Held Instrument for Enhanced Microsurgical Accuracy.- A New Robotic System for Visually Controlled Percutaneous Interventions under CT Fluoroscopy.- A Miniature Instrument Tip Force Sensor for Robot/Human Cooperative Microsurgical Manipulation with Enhanced Force Feedback.- Portable Virtual Endoscope System with Force and Visual Display for Insertion Training.- MR Compatible Surgical Assist Robot: System Integration and Preliminary Feasibility Study.- Needs Assessment for Computer-Integrated Surgery Systems.- Robotic Assist for MR-Guided Surgery Using Leverage and Parallelepiped Mechanism.- Endoscopic Robots.- An Augmentation System for Fine Manipulation.- Endoscopic Robotically Assisted Coronary Artery Bypass Anastomosis on the Beating Heart: Analysis of Quality and Patency.- Distributed Modular Computer-Integrated Surgical Robotic Systems: Implementation Using Modular Software and Networked Systems.- Distributed Modular Computer-Integrated Surgical Robotic Systems: Architecture for Intelligent Object Distribution.- Motion-Based Robotic Instrument Targeting under C-Arm Fluoroscopy.- Plastic and Craniofacial Surgery.- Image-Based 3D Planning of Maxillofacial Distraction Procedures Including Soft Tissue Implications.- Computer-Assisted Orthognathic Surgery: Consequences of a Clinical Evaluation.- PC-based Virtual Reality Surgical Simulation for Orthognathic Surgery.- A 3-D System for Planning and Simulating Minimally-Invasive Distraction Osteogenesis of the Facial Skeleton.- Modeling for Plastic and Reconstructive Breast Surgery.- Development of 3D Measuring Techniques for the Analysis of Facial Soft Tissue Change.- Accuracy of a Navigation System for Computer-Aided Oral Implantology.- A 3D Finite Element Model of the Face for Simulation in Plastic and Maxillo-Facial Surgery.- Orthopaedics.- Simulation of Patellofemoral Joint Reconstruction Surgery on Patient-Specific Models.- A Strain-Energy Model of Passive Knee Kinematics for the Study of Surgical Implantation Strategies.- Computer-Assisted Anatomical Placement of a Double-Bundle ACL through 3D-Fitting of a Statistically Generated Femoral Template into Individual Knee Geometry.- Post-operative Measurement of Acetabular Cup Position Using X-ray/CT Registration.- Intraoperative Simulation and Planning Using a Combined Acetabular and Femoral (CAF) Navigation System for Total Hip Replacement.- Fixation-Based Surgery: A New Technique for Distal Radius Osteotomy.- A Computer-Assisted ACL Reconstruction System Assessment of Two Techniques of Graft Positioning in ACL Reconstruction.- A Classification Proposal for Computer-Assisted Knee Systems.- A Navigation System for Computer Assisted Unicompartmental Arthroplasty.- An Augmented Reality Navigation System for Computer Assisted Arthroscopic Surgery of the Knee.- Repeatability and Accuracy of Bone Cutting and Ankle Digitization in Computer-Assisted Total Knee Replacements.- Double-Bundle Anatomic ACL-Reconstruction with Computer Assisted Surgery: An In-Vitro Study of the Anterior Laxity in Knees with Anatomic Double-Bundle versus Isometric Single-Bundle Reconstruction.- Measurement of Pelvic Tilting Angle During Total Hip Arthroplasty Using a Computer Navigation System.- Efficacy of Robot-Assisted Hip Stem Implantation. A Radiographic Comparison of Matched-Pair Femurs Prepared Manually and with the Robodoc® System Using an Anatomic Prosthesis.- Surgical Navigation for THR: A Report on Clinical Trial Utilizing HipNav.- Description of Anatomic Coordinate Systems and Rationale for Use in an Image-Guided Total Hip Replacement System.- XIMIT X-Ray Migration Measurement Using Implant Models and Image Templates.- Construction of 3D Shape Models of Femoral Articular Cartilage Using Harmonic Maps.- Virtual Fluoroscopy: Safe Zones for Pelvic Screw Fixations.- Three-Dimensional Measurement of the Femur Using Clinical Ultrasound: Developing a Basis for Image Guided Intramedullary Nail Fixation of the Femur.- Percutaneous Computer Assisted Iliosacral Screwing: Clinical Validation.- Milling versus Sawing: Comparison of Temperature Elevation and Clinical Performance During Bone Cutting.