Examines the structural diversity of the Fc domain for IgG and IgE Explores the role of Fc receptors in the context of infectious, autoimmune, and neoplastic disorders Provides comprehensive information on Fc receptor pathways as an essential part of the immune response

Autorentext

Jeffrey V. Ravetch

Theresa and Eugene M. Lang Professor

Department Leonard Wagner Laboratory of Molecular Genetics and Immunology

Rockefeller University

1230 York Avenue, Box 98

New York, NY 10021, USA

ravetch@mail.rockefeller.edu

Falk Nimmerjahn

Professor for Immunology and Genetics

Chairman of the Institute of Genetics

Head of the Department of Biology

Department of Biology

University of Erlangen-Nuernberg

Erwin-Rommelstr. 3 91058 Erlangen, Germany

falk.nimmerjahn@fau.de

Inhalt

IgG Fc receptors: evolutionary considerations.- Role of FcgRs in Antibody Based Cancer Therapy.- Anti-inflammatory Activity of IgG-Fc.- IgG Fc glycosylation in human immunity.- IgE Glycosylation in Health and Disease.- Immune Complex Vaccination.- Fc receptors in anti-microbial protection.