Viral Genome Packaging focuses on the process of genome "packaging" within a pre-formed viral procapsid. The chapters of this book concentrate on the biochemistry, enzymology and structural aspects of the genome packaging machinery. This book defines a broad mechanistic basis for the process across the prokaryotic and eukaryotic border, and for DNA and RNA viruses. The biochemical, biophysical and structural aspects of genome packaging are examined in detail.

The only book to comprehensively cover virus assembly, and specifically the process of genome encapsidation Can be used in graduate courses in virology

Klappentext

Viral Genome Packaging focuses on the process of genome "packaging" within a pre-formed viral procapsid. The chapters of this book concentrate on the biochemistry, enzymology and structural aspects of the genome packaging machinery. This book defines a broad mechanistic basis for the process across the prokaryotic and eukaryotic border, and for DNA and RNA viruses. The biochemical, biophysical and structural aspects of genome packaging are examined in detail.

Inhalt
Viral Genome Packaging Machines.- Bacteriophage Lambda Terminase and the Mechanism of Viral DNA Packaging.- DNA Packaging in Bacteriophage T4.- T3/T7 DNA Packaging.- DNA Packaging by Bacteriophage P22.- Bacteriophage SPP1 DNA Packaging.- The ø29 DNA Packaging Motor.- Encapsidation of the Segmented Double-Stranded RNA Genome of Bacteriophage ?6.- Cleavage and Packaging of Herpes Simplex Virus 1 DNA.