The Boerhaave Committee for postgraduate Medical Education decided to organize a course on cancer treatment covering selected solid tumors, in which they felt important chan ges were emerging in the basic biologic, diagnostic and therapeutic concepts. Current management of cancer patients is intimately dependent on precise morphologic diagnosis, clinical staging and the proper application of all treat ment modalities. Many prominent investigators and clinicians of major can cer centers in the United States, Canada, and Europe con tributed by lecturing and during the panel discussions. This book is the tangible outcome of the productive ex changes during the meeting held December 6-8, 1979. In ovarian cancer the usefulness of histologic grading in determining prognosis has become clear. The most impor tant advance for the management of the patient is th- careful staging procedure, based on new concepts of tumor spread coupled with treatment tailored to the extent of disease. Survival appears to be directly related to the extent of the tumor mass. This has resulted in description and application of optimal cyto-reductive surgery. Radiotherapy and chemotherapy can both effectively eradi cate small amounts of tumor.

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One: Ovarian Cancer.- 1. Cytoreductive surgical treatment in the management of advanced ovarian cancer.- 2. Post-operative radiotherapy in ovarian cancer stages I and II.- 3. Radiotherapy in the treatment of stages III and IV.- 4. Cisplatin therapy of ovarian cancer.- 5. Hexamethylmelamine and cisplatinum combinations in the treatment of ovarian cancer.- 6. Current treatment and new prospects.- 7. Second-look laparotomy and prognosis related to extent of residual disease.- 8. Long term survival following chemotherapy for advanced epithelial ovarian carcinoma.- 9. New drugs in ovarian cancer: in vitro. Phase II screening with the human tumor stem cell assay.- 10. New drugs in the treatment of ovarian cancer.- 11. Current and future management of ovarian cancer Paneldi scussion: Chairman.- Two: Testicular Cancer.- 12. Role of surgery in the management of nonsemino- matous germ cell tumors of the testis.- 13. Role of radiotherapy in the treatment of testicular cancer.- 14. Combination of chemotherapy and radiotherapy in the treatment of testicular cancer.- 15. Testicular cancer: The Indiana University experience.- 16. The VAB schemes of treatment for germ cell tumors.- 17. Combination of chemotherapy and debulking surgery.- 18. New leads from the laboratory for treating testicular cancer.- 19. New drugs in the treatment of testicular cancer.- 20. An update of the Dutch Multicenter PVB-study in disseminated testicular nonseminomas.- 21. Chemotherapy of advanced malignant teratomas.- 22. Current and future management of testicular cancer Paneldi scussion: Chairman.- Three : Osteosarcoma.- 23. Classification and prognosis of osteosarcoma.- 24. Surgery and adjuvant chemo-immunotherapy in osteosarcoma: Review of treatment at the National Cancer Institute.- 25. The role of radiotherapy in the treatment of the primary and in adjuvant therapy.- 26. Chemotherapy of osteosarcoma An overview.- 27. The succesful management of metastatic osteogenic sarcoma: A model for the treatment of primary osteogenic sarcoma.- 28. Current and future management of osteosarcoma Paneldiscussion : Chairman.- Four: Soft Tissue Sarcoma.- 29. Soft tissue sarcoma Classification and prognosis.- 30. Surgery and adjuvant radiation-chemo-immunotherapy in soft tissue sarcomas: Results of treatment at the National Cancer Institute.- 31. Soft tissue sarcoma: Treatment of advanced disease in the Royal Marsden Hospital.- 32. Treatment of advanced soft tissue sarcomas in adults: Past, present, and future.- 33. Treatment of childhood soft tissue sarcomas.- 34. New drugs for the treatment of soft tissue sarcomas.- 35. Current and future management of soft tissue sarcoma Paneldiscussion: Chairman.