THE TESTIS: FROM STEM CELL TO SPERM FUNCTION presents the proceedings of the XVth Testis Workshop held in Louisville, Kentucky. The proceedings review the state-of-the-art analysis of testis development and function.

Inhalt
Preface.- Contributors.- Prologue.- 1. Unlocking the Mysteries of Male Reproductive Function: How Far Have We Come and Where Are We Going?.- 2. Spermatogenesis After the Millennium.- I. Testis Development and Differentiation.- 3. Sry and the Testis: Molecular Pathways of Organogenesis.- 4. MIS Actions in the Developing Testis.- 5. Regulation of the Differentiation of the Undifferentiated Spermatogonia.- 6. Regulation of Growth and Survival in the Mammalian Germline.- II. Paracrine and Endocrine Interactions.- 7. Synthesis, Fate, and Proposed Function of Clusterin (SGP-2) in the Testis.- 8. HRT for the Aging Male: A Therapy That Has Come of Age?.- 9. Androgen Replacement in Young Men.- III. Genetics and Cell Biology of Spermatogenesis.- 10. Developmental Genetics of Spermatogenesis in the Nematode Caenorhabditis elegans.- 11. Regulation of Meiosis and Spermatid Differentiation in Drosophila Primary Spermatocytes.- 12. HSP70 Chaperones in Spermatogenesis.- 13. Characterization of the Testicular Histone-Binding Protein, NASP.- 14. The Actin-Bundling Protein Espin and Its Role in the Ectoplasmic Specialization.- IV. Epididymal Maturation and Fertilization.- 15. Regulation of Epididymal Function by Testicular Factors: The Lumicrine Hypothesis.- 16. Aging Causes Structural and Functional Alterations in the Epididymis.- 17. The Molecular Basis of SpermEgg Interactions.- V. Genetic Defects and Remedies.- 18. Heritable Sperm Degeneration in the Domestic Fowl.- 19. The DAZ Gene Family and Germ-Cell Development.- 20. Genetic Defects of Male Infertility and ICSI.- 21. Spermatids: Clinically Useful Gametes?.- 22. Effect of Embryo Culture on Imprinted Gene Expression in the Preimplantation Mouse Embryo.- Author Index.