Klappentext

Techniques and Protocols for Evaluating Nanosystems: From Design and Development to Biological Applications is a comprehensive guide on the main techniques used in the characterization of nanoparticulate systems. Covering a wide range of techniques such as thermal analysis, imaging, light scattering, analytical, optical spectroscopic, and statistical and AI-based optimization techniques, the book provides a thorough explanations of each technique, highlighting their advantages and limitations and providing characterization protocols and case studies for their application. Special attention is given to the regulatory and pharmaceutical industry requirements.

This book offers researchers and advanced students a valuable resource on application of these techniques in the fields of nanotechnology, pharmaceutical technology, and chemical engineering.

Inhalt

1. The properties, the classes, and the applications of nanoparticulate systems
2. Differential Scanning Calorimetry and micro-Differential Scanning Calorimetry
3. Thermogravimetric analysis (TGA)
4. Isothermal Titration Calorimetry (ITC)
5. Dynamic-Static-Electrophoretic Light Scattering
6. Neutron Scattering Techniques
7. Transmission Electron Microscopy
8. Atomic Force Microscopy
9. Confocal Microscopy
10. Analytical Techniques (i.e. HPLC, BET, etc.)
11. Optical spectroscopic techniques (PL, XRD, XPS, etc.)
12. Optical spectroscopic techniques (UV-Vis, FTIR, Raman, etc.)
13. Statistical and AI-Based Optimization Techniques (Taguchi Method, Machine Learning, Data Mining, etc.)
14. Nanotoxicity studies
15. The usage of the techniques of the characterization of nanoparticulate systems in the pharmaceutical industry
16. Characterization techniques for the design and the development nanosimilars and "off-patent" nanomedicines
17. The requirements for the characterization of the nanoparticulate systems from the regulatory authorities
18. Conclusions and future perspectives