This book presents state of the art knowledge on dyslipidemia in stroke, covering both basic and clinical aspects in detail. The focus is in particular on two major themes: the clinical significance of dyslipidemia in stroke and the treatment of dyslipidemia in stroke patients. Readers will find up-to-date information on lipid metabolism, biomarkers, and advances in treatment options, including novel biologic drugs. Specific management considerations and pitfalls are also discussed. The individual components of pathophysiology, treatment, and key issues are addressed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. This book is timely in bringing together within one volume the most important current knowledge on dyslipidemia in stroke. It will be invaluable for stroke physicians, pharmacists, and students seeking to acquire up-to-date knowledge.

Presents state of the art knowledge Covers both basic and clinical aspects in detail Evaluates currently available treatment modalities Discusses a range of specific considerations Provides clear management guidance

Autorentext

Seung-Hoon Lee, MDProfessor, Department of Neurology, Seoul National University Hospital, Seoul, Republic of KoreaChairman, Korean Cerebrovascular Research Institute, Republic of Korea Min Kyoung Kang, MD Department of Neurology, Uijeongbu Eulji Medical Center

Gyeonggi, Republic of Korea

Inhalt

Part 1 Basic Science: Dyslipidemia and Stroke.- 1 Role of Dyslipidemia in Atherosclerosis.- 2 Effects of Dyslipidemia on the Cerebral vessels.- Part 2 Clinical Significance of Dyslipidemia in Stroke.- 3 Impact of Dyslipidemia on Ischemic Stroke.- 4 Dyslipidemia and Hemorrhagic Stroke.- 5 Clinical biomarkers of Dyslipidemia. Part 3 Treatment of Dyslipidemia in Stroke Patients.- 6 Therapeutic Lifestyle Modification.- 7 Statins.- 8 Ezetimibe.- 9 Fibrate and Niacin.- 10 Fish Oils.- 11 PCSK9 inhibiting monoclonal antibodies.- 12 PCSK9 inhibiting siRNA.- 13 Understanding of Clinical Practice Guidelines for Dyslipidemia.- Part 4 Management of Dyslipidemia in Clinical Practice of Stroke.- 14 Practical Management of Dyslipidemia in Stroke Patients.- 15 Practical Dyslipidemia Management in Stroke-specific Situations.- 16 Dyslipidemia in Women: Etiology and Management.- 17 Safety Considerations of Pharmacological Treatment.