This book presents state of the art knowledge on diabetes in stroke, covering both basic and clinical aspects in detail. The focus is in particular on two major areas: general knowledge of diabetes and diabetes from a stroke neurologist's perspective. Readers will find up-to-date information on glucose metabolism, the pathophysiology of diabetes, the clinical significance of diabetes in stroke, the differential influence of diabetes on stroke mechanisms, principles of diabetes care, advances in treatment options, and clinical practice in the real world. The individual components of pathophysiology, management, and key issues are fully addressed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. The book is timely in bringing together within one volume the most important current knowledge on diabetes in stroke. It will be invaluable for stroke physicians, epidemiologists, and students seeking to acquire up-to-date knowledge.

Presents state of the art knowledge on diabetes in stroke Reviews and evaluates the available therapeutic modalities Covers both basic and clinical aspects in detail and provides guidance on the management of diabetes in stroke

Autorentext

Seung-Hoon Lee

Department of Neurology

 Seoul National University Hospital

  Seoul, Korea (Republic of)

 sb0516@snu.ac.kr

Dong-Wan Kang

 Department of Neurology

 Seoul National University Hospital

 Seoul, Korea (Republic of)

dwkang0201@gmail.com

Inhalt

Part 1 Basic Science: diabetes and stroke.- 1 Glucose metabolism.- 2 Pathophysiology and risk factors of diabetes.- 3 Macro- and microvascular complications of diabetes.- 4 Hyperglycemia in acute stroke.- Part II Clinical significance of diabetes in cerebro-cardiovascular disease.- 5 Clinical impact of diabetes mellitus in cardiovascular disease.- 6 Epidemiology of stroke patients with diabetes.- 7 Differential influence of diabetes on stroke subtypes.- Part III. Treatment of diabetes.- 8 Principles of diabetes care and lifestyle modification.- 9 Metformin and sulfonylurea.- 10 Insulin therapy.- 11 Thiazolidinedione (TZD).- 12 Dipeptidyl peptidase-4 inhibitors.- 13 SGLT2 inhibitors.- 14 Glucagon-like peptide-1 receptor agonist.- 15 Standard pharmacological treatment of diabetes based on the guidelines.- 16 Future therapies of diabetes.- Part IV Actual clinical practice in patients with diabetes.- 17 Diabetes in pregnancy.- 18 Glucose lowering strategy in acute stroke.- 19 Management of acute complications of diabetes mellitus.- 20 Long-term glycemic control for stroke survivors.