This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs , and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.

International expertise and experience in one volume Comprehensive; provides background and current information and applications Cogent organization, by tissue type or disease, discusses new concepts, future directions

Autorentext
Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC).

Inhalt

Stem cells heterogeneity.- Heterogeneity in epiblast stem cells.- Progenitor cell heterogeneity in the adult carotid body germinal niche.- Planarian stem cell heterogeneity.- The cellular origin of Barrett's esophagus and its stem cells.- Pluripotent stem cell heterogeneity.- Sarcoma stem cell heterogeneity.- Heterogeinity in adipose derived stem cells.- Unveiling stem cell heterogeneity towards the development of salivary gland regenerative strategies.- Heterogeneity of human mesenchymal stromal/stem cells.- Mitochondrial heterogeneity in stem cells.- The heterogeneity of renal stem cells, and their interaction with bio- and nano-materials.- Index.