This comprehensive, up-to-date guide covers diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. Includes risk analysis, genetic counselling, predictive testing and organisation of the cancer genetics service.

This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. It is fully updated with much molecular, screening and management information. It covers risk analysis and genetic counselling for individuals with a family history of cancer. It also discusses predictive testing and the organisation of the cancer genetics service. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action. It aims to provide such details in a practical format for geneticists and clinicians in all disciplines.

Provides a wide-ranging perspective on health care provision with an international authorship Deals with genetic counselling for families at risk of cancer susceptibility Practical and comprehensive guide to management of familial cancer susceptibility

Klappentext

A Practical Guide to Human Cancer Genetics, 4th edition, is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. This fully updated new edition covers risk analysis and genetic counseling for individuals with a family history of cancer, and includes a discussion of predictive testing and the organisation of the cancer genetics service. There is also information about the genes causing Mendelian cancer predisposing conditions and their mechanisms of action.

This book is an invaluable reference source for students, general practitioners, geneticists and specialist clinicians in all disciplines.

Inhalt

1. Central Nervous System.- 2. Eye.- 3. Cardiorespiratory System and Thorax.- 4. Endocrine System.- 5. Gastrointestinal System.- 6. Reproductive System.- 7. Urinary System.- 8. Blood and Lymph.- 9. Musculoskeletal System.- 10. Skin.- 11. Inherited Cancer-Predisposing Syndromes.