Autorentext

Sabela Carballal Ramil, Teaching Assistant, Faculty of Medicine, University of Barcelona. Area Specialist Physician, Gastroenterology Department, Hospital Clinic Barcelona.

Joaquín Cubiella Fernández, Teaching Assistant, Faculty of Medicine, University of Santiago de Compostela, A Coruña. Area Specialist Physician, Digestive System Department, Ourense University Hospital.

Klappentext

Digestive tumors are one of the leading causes of cancer mortality, with their prognosis depending significantly on the stage at which they are detected. Therefore, preventive measures are especially important in individuals with genetic alterations, hereditary syndromes, or premalignant lesions, due to their high risk of developing tumors. However, a lack of knowledge and the absence of a multidisciplinary approach and consistency in assessment and follow-up mean that the population considered "high-risk" is not receiving the care it needs.This manual has been created to help solve these shortcomings and provide the necessary knowledge for optimal care in the field of high-risk digestive tumor consultations.

Key features:

• Addresses the molecular and genetic basis of hereditary predisposition to gastrointestinal and pancreatic cancer, develops the psychological and ethical-legal aspects associated with genetic counseling, and describes the skills necessary to carry out this counseling process.
• Examines recognition of the main cancer predisposition syndromes, their prevention, monitoring and therapeutic management.
• Studies the interpretation of diagnostic tests, especially advanced endoscopic techniques, and the endoscopic and surgical treatment of digestive tumors.
• Prepared by leading experts in the field and taking into account all of the necessary disciplines necessary for managing high-risk digestive tumor consultations. High-Risk Digestive Tumour Consultations is aimed at any healthcare professional with an interest in digestive oncology (such as gastroenterologists and oncologists), genetic counselling (geneticists) and the doctor-patient relationship (specialists in internal medicine and advanced practice nursing).

Inhalt

Part I: Basics of High-Risk Digestive Cancer Consultation 1. Genetic diagnosis in hereditary cancer 2. Ethical and legal aspects of genetic counselling 3. Organization of a high-risk consultation 4. Overview of endoscopy in the prevention of digestive tumors 5. Advanced endoscopy in the detection, characterization, and treatment of digestive tumors Part II: Hereditary Colorectal Cancer not Associated with Polyposis 6. Hereditary non-polyposis colorectal cancer 7. Lynch syndrome and other causes of DNA repair system disorders 8. Hereditary colorectal cancer beyond Lynch syndrome Part III: Colorectal Cancer Associated with Polyposis 9. Colorectal polyposis 10. Adenomatous polyposis: definition and variants 11. Adenomatous polyposis: preventive strategies 12. Hamartomatous polyposis Part IV: Non-Hereditary Forms of High-Risk Colorectal Cancer 13. Non-hereditary familial colorectal cancer 14. Associated colorectal cancer inflammatory bowel disease 15. Serrated polyposis syndrome 16. Non-hereditary adenomatous polyposis and individuals with multiple polyps 17. Post-resection surveillance of adenomatous and serrated polyps Part V: Familial and Hereditary Gastric Cancer 18. Hereditary gastric cancer: evaluation and diagnosis 19. Diffuse hereditary gastric cancer 20. Other forms of hereditary gastric cancer 21. Familial gastric cancer and prevention strategies in gastric cancer Part VI: Familial and Hereditary Pancreatic Cancer 22. Associated Syndromes to hereditary pancreatic cancer 23. Hereditary pancreatic cancer: evaluation and diagnosis 24. Familial pancreatic cancer