This book seeks to represent the main concepts and theories related to psychoneuroimmunology with the aim of their application in clinical settings and formation of novel theories to further elucidate the mutual connection of the psyche and the physiology of humans' body. Psychoneuroimmunology, as an integration of popular research fields such as psychology, immunology, neurology, and neuroscience, is a perfect example of interdisciplinary and transdisciplinary studies that could potentially result in developing alternative diagnostic tools and treatment strategies besides facilitating the understanding of the pathophysiology of some conditions that might not properly be understood with a single point of view. Considering the stressful lifestyle and the high prevalence of neuropsychiatric, metabolic, and immune-related disorders, psychoneuroimmunology could be the path to the management of these conditions and reduction of the burden of the diseases.

Offers a comprehensive guide to the understanding of the basic concepts of psychoneuroimmunology Includes the latest studies written by internationally renowned experts and scientists in this field Discusses integrated approaches to facilitate the development of novel ideas for interdisciplinary research

Autorentext

Professor Nima Rezaei gained his medical degree (M.D.) from Tehran University of Medical Sciences and subsequently obtained an M.Sc. in Molecular and Genetic Medicine and a Ph.D. in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the full professor of Immunology, vice dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and head of the Research Center for Immunodeficiencies. He is also the founder of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has contributed to the publication of more than 1500 scientific papers in international journals, editing more than 30 books, participated in several international collaborative projects, and delivered invited lectures in many conferences. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than 40 international journals. 

Dr. Niloufar Yazdanpanah gained her medical degree (M.D.) from Tehran University of Medical Sciences. In 2022, she received the title of Best Undergraduate Researcher Student of the Year at the Tehran University of Medical Sciences and also received the same award in Children's Medical Center Hospital; in 2023, she was awarded as the First-Rank Razi Medical Award, the most prestigious national award in medical sciences. She is currently a research assistant at Research Center for Immunodeficiencies. She has contributed to many projects and articles; she was the editorial assistant in a number of books in the field of translational immunology. 

Inhalt

1 Introduction on psychoneuroimmunology and diseases.- 2 The role of the immune system in creating depression, PTSD, and psychosis.- 3 The role of plastizicers in the psiconeuroimmunoendocrinology of pyschiatric disroders.- 4 Immunoinflammatory mechanisms in sex-dependent vulnerability to mental disorders.- 5 Study of neuroendocrine-immune interactions in major depression to develop more efficient therapeutic options.- 6 The interaction between the blood brain barrier and T cells and its implication on psychiatric diseases.- 7 The Integrated Role of Toll-like Receptors and Inflammasomes in Neuropsychiatric Disorders.- 8 Role of Regulatory Immune Cells in Psychiatric Disorders.- 9 Cell-mediated immunity in major depressive disorder.- 10 Association of microglia on a neurodevelopmental disorder (maternal immune activation).- 11 Immune cells in the choroid plexus: role in nervous and mental diseases.- 12 Psychoneuroimmunology of Schizophrenia.- 13 Depression in Parkinson's Disease: A trajectory linking gut microbiota and neuroinflammation.- 14 Alzheimer's disease: A complex disease, which needs an interdisciplinary approach.- 15 Alexithymia and Immunity: Where Do We Stand Today.- 16 Sleep disorders in viral infection/virus-induced inflammation.- 17 Neuroimmune interactions in chronic pain: Focus on microglia and macrophages.- 18 Neurological and psychological components of alcohol-dependent states.- 19 Neuroendocrine-immune related content with implications to development of autoimmunity.- 20 Psychoneuroimmunology of diabetes mellitus: The possible association.- 21 Psychoneuroimmunology in rheumatic diseases.- 22 The psychosocial impact of immune mediated skin diseases.- 23 Psychoneuroimmune aspects of atopic dermatitis.- 24 Chronic urticaria through the prism of psycho-neuro-immunology: another Gordian Knot to solve.- 25 Neuro-immune Communication in Cancer.- 26 Turkey Psychoneuroimmunology and Cancer: The New Insights for Improving Immune Activation and Quality of Life in Cancer Patients.- 27 Practical applications of mindfulness, hypnotherapy and guided visualisation as part of a psychoneuroimmunological approach in supporting cancer therapies.- 28 Interaction between neuroimmune response and GI cancer (by now there is no evidence of any recommendation in practice).- 29 Neuroinflammation and behavioral abnormalities during pulmonary tuberculosis, the potential mechanisms and therapy.- 30 PsychoNeurological and Immunological aspects of Cushing's syndrome.- 31 Infertility through the Lens of Psychoneuroimmunology: Revealing the Impact of Stress and Immune Disruption.- 32 Neuroimmunology of endometriosis associated pain and its psychological aspects.- 33 Addiction to indoor ultraviolet tanning.