Prenatal and Postnatal Determinants of Development

This volume provides readers with an introduction to all the methods and major approaches now being used to study the structural and functional development of the brain. Prenatal and Postnatal Determinants of Development explores early anatomical development, the emergence of function and the processes that lead to damage and repair of the growing and immature brain. Chapters are divided into three sections covering development, programming and stress, and brain damage-causes and consequences. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Prenatal and Postnatal Determinants of Development aims to ensure successful results in the further study of this vital field.

Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts

Inhalt

Investigating Early Formation Of The Cerebral Cortex by In Utero Electroporation Methods And Protocols.- In Utero Electroporation Methods in the Study of Cerebral Cortical Development.- Isolation of GABAergic Cortical Neurons and Implications for Cell Transplantation Strategies in the Nervous System.- Advanced EEG and MRI Measurements to Study the Functional Development of the Newborn Brain.- Cerebral Blood Flow Measurements in the Neonatal Brain.- Fetal Sleep and Spontaneous Behaviour in Utero: Animal and Clinical Studies.- Circadian Rhythms in the Fetus and Newborn-Significance of Interactions with Maternal Physiology and the Environment.- Prenatal Programming of the Mesolimbic Reward Pathway and Food Preferences.- Perinatal and Postnatal Determinants of Brain Development Recent Studies and Methodological Advances.- Models of Perinatal Compromises in the Guinea Pig - Their Use in Showing the Role of Neurosteroids in Pregnancy and the Newborn.- Placental Transport and Metabolism: Implications for the Developmental Effects of Selective Serotonin Reuptake Inhibitors (SSRI) Antidepressants.- Studies on the Effects Prenatal Immune Activation on Postnatal Behaviour Models of Developmental Origins of Schizophrenia?.- Oligodendrocytes: Cells of Origin for White Matter Injury in the Developing Brain?.- Prenatal Determinants of Brain Development Recent Studies and Methodological Advances.- Using Pregnant Sheep to Model Developmental Brain Damage.- A Procedure for Inducing Seizures in the Postnatal Rat.- Origin and Detection of Neonatal Seizures Animal and Clinical Studies.