This book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to one-size-fits-all treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment.

The book's four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors' experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer.

Presents translational research and its application in gastric cancer Describes four promising fields of cancer treatment

Autorentext
Jia Wei, MD, PhD, is an associate professor at Nanjing University and the vice director of Clinical Cancer Institute of Nanjing University. She is now working as an oncologist in the Comprehensive Cancer Center, Affiliated Drum Tower Hospital to Medical School of Nanjing University.

Baorui Liu, MD, PhD, is a professor at Nanjing University and director of the Clinical Cancer Institute of Nanjing University. He is also the director of the Comprehensive Cancer Center of Drum Tower Hospital.

Inhalt

Molecular pathology of hereditary gastric cancer.- Genetics and molecular signature of gastric cancer.- Circulating tumor cells in gastric cancer.- Customized chemotherapy in advanced gastric cancer.- Targeted therapy in advanced gastric cancer.- Laparoscopic surgery and robotic surgery.- Radiotherapy in peritoneal metastatic gastric cancer.- Personalized intraperitoneal strategy in gastric cancer.- Checkpoint blockade therapy of gastric cancer.- Adoptive cell therapy of gastric cancer.- Combinational immunotherapy of gastric cancer.- Use of Nanomedicine in the diagnosis of gastric cancer.- Systemic drug delivery.- Local drug delivery.- Drug delivery in synergistic combination with other treatments.