Recent advances in diabetology and therapeutics have changed the outlook of pediatric diabetes. Emphasis on disease-modifying therapies and the use of off-label agents in some cases have pushed the field forward in various areas of endocrinology. This evidence-based book contains the latest findings in diabetes, particularly as it relates to cases in childhood and adolescence. It focuses on cutting edge science to deliver the best thinking in pediatric endocrinology, as well as new revolutionary concepts that will shape the field in the next few decades. The aim of this book is to bring this new knowledge to endocrinologists, general practitioners, trainees, and nurses in a manner that would be easy to read and understand. It provides a robust, evidence-based resource for generalists and specialists worldwide who care for children and adolescents with diabetes mellitus.

Written by an international selection of experts from centers of diabetes care, the content of this volume contains emerging topics, such as precision therapy for diabetes phenotypes, emerging therapies for Wolfram syndrome, emerging diagnostic approaches for cystic fibrosis related diabetes, disease modifying therapies in type 1 diabetes, and the role of high-dose vitamin D therapy in protecting the beta cells of the pancreas. It is intended to provide a deeper understanding of the clinical approaches to the management of diabetes in children and adolescents. Pediatric Diabetes serves as a comprehensive reference of the most timely and influential advances in this field that will guide clinical practice and research for years to come.

Discusses the major types of diabetes mellitus, T1D, T2D, Wolfram syndrome and cystic fibrosis related diabetes Contains up-to-date management strategies for the expanding diabetes phenotypes in an easy-to-read format Provides a better understanding of the clinical approaches to the management of diabetes in children and adolescents

Autorentext

Benjamin Udoka Nwosu

Professor of Pediatrics, Zucker School of Medicine, Hofstra University

Chief of Endocrinology, Cohen Children’s Medical Center

Queens, NY

USA

Ambika P. Ashraf

Professor of Pediatrics, Heersink School of Medicine

Division Director, Pediatric Endocrinology and Diabetes

University of Alabama at Birmingham

Birmingham, AL

USA

Inhalt

Introduction to Pediatric Diabetes Mellitus.- Type 1 Diabetes.- Stages of type 1 diabetes and new interventions teplizumab .- Vitamin D is a key disease-modifying therapy for type 1 diabetes.- Pediatric Hyperglycemic Emergencies.- Type 2 Diabetes.- Neonatal Diabetes.- Maturity-Onset Diabetes of the Young (MODY).- Cystic Fibrosis-Related Diabetes.- Diagnosis and Management of Wolfram Syndrome.- Dyslipidemia in Pediatric Diabetes.- Diabetes in Syndromes of Severe Insulin Resistance.- Precision medicine in diabetes phenotypes.- COVID-19 and Diabetes Mellitus.- High-dose Vitamin D and Non-Skeletal Health.