This book provides a thorough analysis of the complex relationship between obesity and ageing. It sheds light on the shared physiological pathways and biological modulators that accelerate ageing in the context of obesity. With the global population ageing and obesity rates increasing, understanding these connections is crucial for public health.

The chapters cover key topics such as the role of gut microbiota, and the impact of metabolic inflammation on health and lifespan. Expert contributors provide critical analyses and evidence-based recommendations for managing obesity to promote healthy ageing. Readers will encounter discussions on dietary patterns, the Mediterranean diet, and innovative interventions like caloric restriction mimetics and gerobiotics.

This volume is an essential resource for researchers, healthcare professionals, and policymakers interested in the intersection of obesity and ageing. It offers valuable insights into the biological causes of these conditions and practical strategies for improving health outcomes in older adults. Whether you are a scholar in gerontology, a clinician, or a public health advocate, this book provides the latest research and expert perspectives to inform your work and enhance your understanding of these pressing issues.

Clarifies the physiological effects of obesity in accelerating ageing Examines how obesity and ageing disrupt inter-organ communication and increase co-morbid conditions in older adults Presents potential lifestyle and pharmacological interventions that combat obesity and promote healthy ageing

Autorentext

Gurcharan Kaur, PhD, is a Former Emeritus Scientist-CSIR and University Honorary Professor, Department of Biotechnology, Guru Nanak Dev University, Amritsar, India. Her research areas and expertise include ageing modulation through intermittent fasting and natural products, especially with respect to the brain health. She is the recipient of IAN-BK Bachhawat Memorial Life Time Achievement Award, and is a Fellow of National Academy of Sciences, India and Indian Academy of Neurosciences along with several other awards and honors in recognition of her contributions in the area of adult brain plasticity in health and disease. She is currently the section editor of the Neurobiology and Ageing section of the journal Biogerontology. ****

Inhalt

Part I: Overview and Evolutionary Perspectives of Obesity in Ageing and Longevity.- 1. Obesity, Ageing, and Longevity: Overview of Obesity Prevalence, Phenotypes and Paradoxes.- 2. Obesity as an aging accelerator.- 3. Genomic Insights into Obesity in the Context of Aging and Longevity.- 4. Epigenomic Perspective of Obesity in the Context of Aging and Longevity.- 5. Neurobiology of Obesity and Aging: Bridging the Gap Between Metabolic and Brain Health.- 6. Examining Aging Related Female Adiposity Through the Endocrine Lens.- 7. Evolutionary aspects of obesity and ageing .- Part II: Biological Modulators of Obesity and Ageing.- 8. Role of obesity-triggered inflammation in aging.- 9. Obesity and Brain Ageing: A Neuroinflammatory Perspective .- 10. Gut Microbiome-Mediated Inter-Organ Crosstalk in Obesity and Aging.- 11. Recent advances in gut microbiome modulation in obesity and longevity .- 12. Beyond the Mouth: The Lifelong Interplay Between Obesity and Oral Diseases.- 13. AgeingObesity Intersections in Hypertension and Renal Injury: Hallmarks, Mechanisms, and Longevity Implications.- 14. Sleep at the intersection of obesity and ageing.- Part III: Management of Obesity for Promoting Healthy Ageing.- 15. Dietary Recommendations for Managing Obesity in Ageing.- 16. Plant versus Animal-Based Foods for the Management of Obesity in Ageing.- 17. The Mediterranean Diet: A Pathway to Successful Aging.- 18. The Role of Inter-organ Communication at the Nexus of Ageing and Obesity: Interventions for Promoting Longevity.- 19. Role of calorie restriction mimetics in the management of obesity in aging.- 20. Pharmacological Interventions for Management of Obesity in Ageing.- 21. Non-pharmacological Interventional strategies for the Management of Obesity in Aging.- 22. Gerobiotics for the management of obesity and epigenetic aging.- 23. Nutraceuticals as interventional tools for the management of obesity in aging.- 24. Molecular Insights into the Preventive and Therapeutic Potential of Soy: Addressing Obesity and Age-Related Diseases.- 25. Chrononutrition for the management of obesity in aging.- 26. Gratitude Practice, Obesity Management, and Healthy Aging.