AMI E. ISKANDRIAN & ERNST E. VAN DER WALL The first edition of this book was published in 1994. Since then important advances have occurred in the field of myocardial viability. This, coupled with increasing interest by the scientific community in the broader issues of its relevance to patient care, suggested to us the need to write the second edition. We are most fortunate to have the help of a distinguished group of experts who have helped shape the field; we appreciate their commitments and contributions. Almost all chapters have been radically modified. Chapter 1 deals with pathophysiology of myocardial hibernation and stunning; Chapter 2 with apoptosis; Chapter 3 with the role of positron emission tomography; Chapters 4 and 5 with the role of single photon emission computed tomography with thallium-201 and technetium agents, respectively; Chapter 6 with the role of SPECT fatty acid imaging; Chapter 7 with the role of SPECT FDG imaging; Chapter 8 with the role of cardiac catheterization angiography; Chapter 9 with the role of echocardiography; Chapter 10 with the role of magnetic resonance imaging; and Chapter 11 with clinical applications. Finally, Chapter 12 provides a short summary.

Klappentext

The second edition of this book was necessary in order to accommodate the rapid rise of interest in this subject. It provides a concise summary of these developments from the bench to the bedside. At stake is the enormous importance of the issue at hand: how to select the patient with severe left ventricular dysfunction who may benefit from coronary revascularization. This is the crux of the matter, knowing that medical therapy in these patients carries a poor outcome even with the newer drugs and that cardiac transplantation is possible in only a few. This book should prove to be a valuable aid to those providing the technical aspects of procedure as well as those who manage such patients, physicians and surgeons alike. It should be in every medical library and on the desk of every medical student, internist, cardiologist, cardiac surgeon, anesthesiologist, nuclear medicine specialist and radiologist.

Inhalt

1. Hibernating and stunned myocardium: pathophysiological considerations.- 2. Role of apoptosis in myocardial hibernation and myocardial stunning.- 3. Assessment of myocardial viability with positron emission tomography.- 4. Assessment of myocardial viability by thallium-201.- 5. Technetium-99m-labeled perfusion tracers for the detection of myocardial viability.- 6. Fatty-acid SPECT imaging for assessment of myocardial viability.- 7. Role of FDG SPECT in viability assessment.- 8. Detection of myocardial viability by angiographic methods.- 9. Echocardiographic assessment of reversible left ventricular dysfunction.- 10. Role of magnetic resonance techniques in viability assessment.- 11. Viability assessment: clinical applications.- 12. Summary by the editors.