This book reviews developments in molecular genetics, showing how they have been adopted in clinical practice. The authors simplify complex genetic concepts and focus on patient related issues. The aim is to help shorten the time from lab bench to bedside.

Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual's specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside.

All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

All chapters are written by experts in their fields The authors simplify complex genetic concepts Focus on practical patient related issues Includes supplementary material: sn.pub/extras

Autorentext

D. Hunter Best
University of Utah School of Medicine, Salt Lake City, UT, USA

Jeffrey J. Swensen
University of Utah School of Medicine, Salt Lake City, UT, USA

Inhalt
Molecular Genetic Testing in the Genomic Era.- Array Comparative Genomic Hybridization in Cytogenetics and Molecular Genetics.- Pharmacogenomics: Tailoring Treatment Based on Genotype.- Somatic Alterations and Targeted Therapy.- Genome Wide Association Studies in Disease Risk Calculation: The Role of Bioinformatics in Patient Care.- Presymptomatic Genetic Testing: Shifting the Emphasis from Reaction to Prevention.- Prenatal Testing: Screening, Diagnosis and Preimplantation Genetic Diagnosis
Eugene Pergament.- Newborn Screening for Metabolic Disorders.- The Role of Genetic Counseling in Everyday Medical Practice.- Direct-to-Consumer Genetic Testing.