This text covers the latest in genomic medicine as exemplified by the molecular pathology of hematologic malignancies. Topics include complexity of genomic lesions, new WHO classification of hematologic neoplasms, prognostic value of molecular tests and more.

Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies. This timely volume will update physicians on the complexities of genomic lesions, as well as offer an integrated framework encompassing molecular diagnosis, the new WHO classification of hematologic neoplasms with focus on molecular pathology, prognostic value of molecular tests, and molecular monitoring of response to gene-targeted therapy. As such, it will be of great value to hematologists, oncologists, pathologists, internal medicine and pediatric specialists, as well as bioscientific staff and laboratorians in private hospitals and academic institutions.

Prognostic value of molecular tests Offers an integrated framework encompassing molecular diagnosis Written by experts in the field Includes supplementary material: sn.pub/extras

Inhalt

Chapter 1: Molecular techniques used in Hematopathology.- Chapter 2: Cytogenetics techniques used in Hematopathology.- Chapter 3: The molecular component of the new WHO classification of hematologic malignancies.- Chapter 4: Molecular pathology of pediatric acute leukemias.- Chapter 5: Molecular pathology of adult acute leukemias.- Chapter 6: Molecular pathology of lymphomas.- Chapter 7: Molecular pathology of chronic myeloproliferative neoplasms.- Chapter 8: Molecular pathology of CLL.- Chapter 9: Targeted therapy in hematologic malignancies.- Chapter 10: MicroRNAs in hematologic malignancies.