The gold-standard reference on the discovery, development, and use of crop protection compounds

In the newly revised fourth edition of "Modern Crop Protection Compounds", a team of distinguished researchers provides an exhaustive overview of today's most important crop protection compounds. Divided into four volumes, dedicated to herbicides, fungicides, and insecticides, the authors explain the invention and development of agrochemicals, their chemistry, mode of action, physicochemical properties, structure-activity relationships, biological and safety profile, industrial synthesis, commercial use, and resistance management, bringing together the most important agrochemical information in a single, comprehensive source.

Building on the success of the previous editions, the four volumes cover:

• A thorough introduction to the individual modes of action and resistance evolution of agrochemicals, classified by international committees

• Comprehensive discussions of the newest herbicides, fungicides, and insecticides, up to those released in 2024

• Brand-new material, including entirely new chapters, with revised and updated content reflecting the latest research advances

• Contributions by some of the leading names in the international agrochemical industry

Perfect for researchers in industry working in the area of agrochemical research and development, mainly in the plant protection industry, this four-volume set will also benefit organic chemists at universities, as well as professionals on advisory boards, and with societies and governmental authorities.

Autorentext
Peter Jeschke was a senior fellow in research and development in Pest Control Chemistry at Bayer AG Crop Science in Germany, from 1997 until his retirement in 2022.He is also an honorary professor at the Heinrich Heine University Düsseldorf, Germany. He has more than 250 patent applications and publications to his name, and he is an Associate Editor for "Pest Management Science" of the Society of Chemical Industry (UK) and also a member of the Editorial Advisory Board for the "Ullmann's Encyclopedia of Industrial Chemistry" (Wiley-VCH).

Clemens Lamberth retired in 2024 after more than 30 years as a senior principal scientist in the chemical research department of Syngenta Crop Protection AG in Switzerland. He is specialized in the discovery of fungicides and is the inventor of the fungicide mandipropamid. He is the author of ca. 100 peer-reviewed publications and book chapters, 120 patents, and edited the two Wiley-VCH books "Bioactive Heterocyclic Compound Classes" and "Bioactive Carboxylic Compound Classes". In 2018, he received the Senior Industrial Science Award from the Swiss Chemical Society.

Beth Lorsbach is the Global Head of Innovation and Development at Nufarm in Indianapolis, USA. She is responsible for delivering innovative and disruptive solutions to solve farmers' needs as Nufarm pivots to become an agriculture innovator. She also provides technical, personnel, and organizational management of the chemistry functional groups whose focus is to discover and characterize novel active ingredients for commercial development. She has authored over 94 patent applications, 23 external publications, and 31 conference presentations. She received the 2015 Rising Star Award from the American Chemical Society (ACS), and was named a 2019 ACS Fellow.

Inhalt
Preface

VOLUME 1: HERBICIDES
Overview

1. HRAC: Mode of Action Classification and Resistance Development Risk of Herbicides
2. Acetohydoxyacid Synthase Inhibitors (AHAS/ALS)
3. Protoporphyrinogen IX Oxidase Inhibitors
4. Herbicides with Bleaching Properties
5. New Auxin Mimics and Herbicides
6. Herbicides Disturbing the Synthesis of Very Long-Chain Fatty Acids
7. Inhibitors of Cellulose Biosynthesis
8. Safeners for Herbicides
9. Genetically Modified Herbicide Tolerant Crops
10. Microtubulin Assembly Inhibitors (Pyridines)
11. Acetyl-CoA Carboxylase Inhibitors
12. Homogentisate Solanesyltransferase (HST) Inhibitors: Cyclopyrimorate
13. Solanesyl Diphosphate Synthase Inhibitors: Aclonifen
14. Inhibitors of the Deoxy-D-Xylulose Phosphate Synthase (DOXP Synthase)
15. Fatty Acid Thioesterase Inhibitors
16. Validation of Dihydroorotate Dehydrogenase as a Herbicide Target: Discovery of Tetflupyrolimet
17. Photosynthesis Inhibitors: Regulatory Aspects, Reregistration in Europe, Market Trends, and New Products
18. New Aspects of Plant Regulators

VOLUME 2: FUNGICIDES
Overview
19. FRAC Mode-of-action Classification and Resistance Risk of Fungicides.
20. Fungicides Acting on Oxidative Phosphorylation
21. Fungicides Acting on Amino Acid and Protein Synthesis: Anilinopyrimidines - Assumed Methionine Biosynthesis Inhibitors
22. Fungicides Acting on Signal Transduction
23. Fungicides Acting on Mitosis and Cell Division: Zoxamide, an Antitubulin Fungicide for Control of Oomycete Pathogens
24. Sterol Biosynthesis Inhibitors
25. Carboxylic Acid Amide (CAA) Fungicides
26. Fluopicolide: An Anti-oomycete Fungicide with a Unique Mode of Action
27. Melanin Biosynthesis Inhibitors
28. Modern Powdery Mildew Fungicides
29. Newest Aspects of Nucleic Acid Synthesis Inhibitors - Metalaxyl-M
30. Host Defense Inducers
31. Oxysterol-binding Protein Inhibitors
32. Quinofumelin and other Dihydroorotate Dehydrogenase Inhibitors
33. Pyridachlometyl and other Tubulin Dynamics Modulators
34. Aminopyrifen and other GPI-anchored Wall Transfer Protein Inhibitors
35. Fungicides with Unknown Mode of Action

VOLUMES 3A AND 3B: INSECTICIDES
Overview
36. IRAC: Insecticide Resistance, and Mode-of-Action Classification of Insecticides
37. Insect Molting and Metamorphosis
38. Chitin Biosynthesis
39. Microbial Disruptors of Insect Midgut Membranes
40. Metabolic Processes
41. Nervous System
42. Chordotonal Organ TRPV Channel Modulators
43. Chordotonal Organ Modulators
44. New Unknown Mode of Action
45. Insecticides Affecting Calcium Homeostasis
46. Vesicular Acetylcholine Transporter Inhibitors
47. Nematicides