This volume presents readers with the latest advancements in microdialysis research. The chapters in this book covers advances in microdialysis for studying neurochemicals, methods for monitoring large molecules, integration with techniques for analyzing neuronal activity, neuronal network dynamics, behavioral mechanisms, and methods for investigating pharmacokinetics. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Authoritative and cutting-edge, Microdialysis is a valuable resource that will contribute to advancing fundamental research through the employment of microdialysis in neuroscience and neuropharmacology.

Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts

Inhalt

Mass Spectrometric Analysis of Neuropeptides in Microdialysis Samples.- Monitoring Neurochemical Changes in the Monkey Brain In Vivo ** Using Microdialysis.- High Temporal Resolution Measurement of Neurotransmitters by Microdialysis Coupled with Capillary Electrophoresis.- Measuring Amyloid- in the Brain Using Microdialysis.- Sampling Large Molecule in Mouse Interstitial Brain Fluid Using Large Pore Microdialysis and Cerebral Open Flow Microperfusion.- Microdialysis with Implantable Optoelectronic Devices.- Studying Neurochemical Mechanisms of Reward using Microdialysis.- Microdialysis Technique to Understand Neurochemical Mechanisms Underlying Memory Formation.- Studying the Neural Basis for Cognition, Memory, and Pathology using Microdialysis.- Pharmacokinetic Studies of Antibodies in Brain Using Microdialysis.- Intra-Operative and Post-Operative Microdialysis for the Study of Brain Tumors, In Situ.- Investigating Biomarkers in Brain Neurosurgery using Microdialysis in Combination with Two-Dimensional Gel Electrophoresis.