Autorentext

Dr. Shijie Liu is a Professor of bioprocess engineering at the State University of New York - College of Environmental Science and Forestry (SUNY ESF). He graduated from Chengdu University of Science and Technology (now Sichuan University) with a BSc. majored in Chemical Engineering. His PhD in Chemical Engineering was earned from University of Alberta. Dr. Liu has 30 years of experience in academia and 5 years of experience in industry. He is a fellow of AIChE, and published over 200 scholarly papers. Earned a spot on the prestigious Top 2% Most Influential Scientists list by Stanford University and Elsevier. Current active research areas include Stem Cells, Fermentation, Biomolecular Kinetics, Bioreactors, Design of Experiments (for Quality Control and Kinetic Analysis). Taught Biomolecular Kinetics, Biochemical Reaction Engineering, Bioprocess Engineering of Reactions, among other courses over the past 20 years.

Klappentext

Bioprocess Engineering of Reactions, Fourth Edition is a systematic and comprehensive resource that explores principles and analysis of reactions within the bioprocess and biotechnology industries. The book provides a step-by-step guide to understanding batch, continuous, and fed-batch reactor operations, reflecting the growth behavior of cells through various phases. It introduces innovative pinch methods for optimizing batch reactors without relying on complex mathematical models while also addressing the intricacies of enzymatic systems and the impact of phase separation on reaction dynamics. Topics covered include biomolecular reaction basics, ideal flow reactors, batch fermentation, continuous culture, and the engineering of cells.

Other sections emphasize sustainability and stability in bioprocess operations while discussing critical factors such as reactivity hazards and biohazards. With a focus on mass and heat transfer, reactor design, and real reactor deviations, the book equips readers with the knowledge to navigate the complexities of bioprocess engineering. It will be an invaluable resource for bioprocess engineers, researchers, and students in in biotechnology, chemical engineering, and molecular biology. By linking reactor operations to specific cell growth patterns and providing insights into optimization strategies, the book also empowers professionals to enhance productivity and ensure safety in their bioprocess endeavors.

Inhalt

1. Introduction
2. Biomolecular Reaction Basics
3. Batch Reactor
4. Ideal Flow Reactors
5. Enzymatic Reaction Engineering
6. Batch Fermentation
7. Continuous Culture
8. Semibatch Cultivation
9. Engineering of Cells
10. Sustainability and Stability
11. Combustion, Reactive Hazard and Bioprocess Safety
12. Mass Transfer Effects: Immobilized and Heterogeneous Reaction Systems
13. Real Reactors and Residence Time Distributions
14. Bioreactor Design & Operation