Autorentext

Elizabeth Allegretto earned a PhD in Biochemistry from the University of Arizona where she did her thesis research on structure function relationships of the vitamin D receptor. She then did post-doctoral work at the University of California San Diego in the Department of Pharmacology working on transcriptional regulation by the jun oncogene. She worked in the pharmaceutical and biotech industries for 12 years in drug discovery research programs targeting nuclear hormone receptors for unmet needs in oncology, women's health, and inflammation, and then embarked on a second career in veterinary medicine, earning a DVM from Tufts Cummings School of Veterinary Medicine (TCSVM). She has worked in small animal private practice and has also taught organic chemistry, biochemistry and biotechnology courses in NJ and biochemistry at TCSVM.

Klappentext

Bridging the gap between basic and clinical science concepts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this updated text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding.

With numerous illustrations and both instructor and student companion websites with updated PowerPoint images, lecture slides, and Snapcasts, Engelking's Textbook of Veterinary Physiological Chemistry, Fourth Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and updated case studies extend the breadth and depth of learning resources.

Inhalt

Section I: Amino Acid and Protein Metabolism

1. Chemical Composition of Living Cells
2. Properties of Amino Acids
3. Amino Acid Modifications
4. Protein Structure
5. Properties of Enzymes
6. Enzyme Kinetics
7. Protein Digestion
8. Amino Acid Catabolism
9. Transamination and Deamination Reactions
10. Urea Cycle (Krebs-Henseleit Ornithine Cycle)
11. Glutamine and Ammonia
12. Nonprotein Derivatives of Amino Acids

Section II: Nucleotide and Nucleic Acid Metabolism
13. Nucleotides
14. Pyrimidine Biosynthesis
15. Purine Biosynthesis
16. Folic Acid
17. Nucleic Acid and Nucleotide Turnover

Section III: Carbohydrate and Heme Metabolism
18. Carbohydrate Structure
19. Polysaccharides and Carbohydrate Derivatives
20. Glycoproteins and Glycolipids
21. Overview of Carbohydrate Metabolism
22. Glucose Trapping
23. Glycogen
24. Introduction to Glycolysis (The Embden-Meyerhoff Pathway (EMP))
25. Initial Reactions in Anaerobic Glycolysis
26. Intermediate Reactions in Anaerobic Glycolysis
27. Metabolic Fates of Pyruvate
28. Hexose Monophosphate Shunt (HMS)
29. Uronic Acid Pathway
30. Erythrocytic Protection from O2 Toxicity
31. Carbohydrate Metabolism in Erythrocytes
32. Heme Biosynthesis
33. Heme Degradation
34. Tricarboxylic Acid (TCA) Cycle
35. Leaks in the Tricarboxylic Acid (TCA) Cycle
36. Oxidative Phosphorylation
37. Gluconeogenesis
38. Carbohydrate Digestion

Section IV: Vitamins and Trace Elements
39. Vitamin C
40. Thiamin (B1) and Riboflavin (B2)
41. Niacin (B3) and Pantothenic Acid (B5)
42. Biotin and Pyridoxine (B6)
43. Cobalamin (B12)
44. Vitamin A
45. Vitamin D
46. Vitamin E
47. Vitamin K
48. Iron
49. Zinc
50. Copper
51. Manganese and Selenium
52. Iodine and Cobalt

Section V: Lipid Metabolism
53. Overview of Lipid Metabolism
54. Saturated and Unsaturated Fatty Acids
55. Fatty Acid Oxidation
56. Fatty Acid Biosynthesis
57. Triglycerides and Glycerophospholipids
58. Phospholipid Degradation
59. Sphingolipids
60. Lipid Digestion
61. Cholesterol
62. Bile Acids
63. Lipoprotein Complexes
64. Chylomicrons
65. VLDL, IDL, and LDL
66. LDL Receptors and HDL
67. Hyperlipidemias
68. Eicosanoids I
69. Eicosanoids II
70. Lipolysis
71. Ketone Body Formation and Utilization
72. Fatty Liver Syndrome (Steatosis)

Section VI: Starvation and Excercise
73. Starvation (Transition into the Postabsorptive Phase)
74. Starvation (The Early Phase)
75. Starvation (The Intermediate Phase)
76. Starvation (The Late Phase)
77. Exercise (Circulatory Adjustments and Creatine)
78. Exercise (si1_e and RQ)
79. Exercise (Substrate Utilization and Endocrine Parameters)
80. Exercise (Muscle Fiber Types and Characteristics)
81. Exercise (Athletic Animals)

Section VII: Acid-Base Balance
82. The Hydrogen Ion Concentration
83. Strong and Weak Electrolytes
84. Protein Buffer Systems
85. Bicarbonate, Phosphate, and Ammonia Buffer Systems
86. Anion Gap
87. Metabolic Acidosis
88. Diabetes Mellitus (Metabolic Acidosis and Potassium Balance)