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Immunogenetics: Advances and Education

  • Kartonierter Einband
  • 296 Seiten
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Proceedings of the NATO Advanced Research Workshop, held in Castá-Papiernicka, Bratislava, Slovak Republic, September 5-9, 1996M. ... Weiterlesen
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Proceedings of the NATO Advanced Research Workshop, held in Castá-Papiernicka, Bratislava, Slovak Republic, September 5-9, 1996

M. BENcovA Slovak Foundation Education in Immunogenetics Kopanice 25, 821 04 Bratislava Slovak Republic Short History of Slovakia After the end of the 5th century, the major part of Central Europe was dominated by Slavs (Slovaks). They had already in the 7th century settle ments in the vicinity of towns Bratislava, Devin, Nitra to create the Slovak's state formation with the name "The Empire of Sam", territory of which corresponded to that of Slovakia of present. The Empire of Sam was also the first state formation in the Central Europe (as present states Czech Republic, Poland, Hungary, Slovakia etc. ) Very important town of this state was Nitra, with the biggest Castle in the Central Europe with his Duke Pribina. The first Church of the Central Europe was built here in the year 830, and it is now considered to be the "Slovak Bethlehem". In the year 880, Nitra also became the first Office of Bishops. Later, the Slovak Duke Pribina and Moravian Duke Mojmir (Moravia corresponded to eastern part of the present Czech Republic) joined their formations to common state "Greate Moravian Empire". The strongest King of the Great Moravian Empire was Svatopluk (864 A. D. ), who spread his empire over Czech Republic, Hungary and part of Poland, Ukraine and eastern Germany of present, which at that time still did not exist as state formations.


The objective underlying this book is educational, aiming to advance the development of immunogenetics/histocompatibility and to encourage the international collaboration that is so necessary for the international transplant programme and for research into the genetic predisposition to develop diseases associated with genes in the HLA complex. The revolution in high-tech molecular biological genome technology has given rise to a prodigious development of molecular techniques for the polymorphism analysis of HLA and the subsequent application of research results in clinical practice. Many new alleles have been discovered and different mechanisms have been shown to generate these new alleles. This has improved both diagnostic efficiency and increased the success of transplantation. Topics covered include HLA associated susceptibility to autoimmune disease. Strategies and efficiency of BMDW and benefit of collaboration. Optimum selection of unrelated bone marrow donor and extension of the pool of suitable donors by determination of possible mismatches. Identification of sibling pairs using microsatellites across the HLA region. HLA in kidney transplantation. Eurotransplant facts and figures. HLA typing from serology to molecular biology. Evolution of DNA based typing in HLA laboratories. HLA and paternity testing.

Preface. Introduction. Part I. Accreditation with European and American Histocompatibility Immunogenetics Organizations. Part II. HLA Diversity and Applications. III. HLA and Diseases. Part IV. Bone Marrow Transplantation. Part V. Transplantation, HLA and non- HLA Aspects. Part VI. Solid Organ and Eye Cornea Transplantation. Part VII. HLA Users. Authors' Index. Subject Index.


Titel: Immunogenetics: Advances and Education
Untertitel: The First Congress of the Slovak Foundation
EAN: 9789401063081
ISBN: 9401063087
Format: Kartonierter Einband
Herausgeber: Springer Netherlands
Genre: Medizin
Anzahl Seiten: 296
Gewicht: 477g
Größe: H240mm x B160mm x T16mm
Jahr: 2013
Auflage: Softcover reprint of the original 1st ed. 1997

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