The wealth of radiological and histopathological images offered inside this book will help clinicians to understand the characteristics of IgG4-related disease in various organs, as well as their clinical and basic medical backgrounds.

IgG4-related disease is a new systemic disease that has only recently been identified and characterized. However, most clinical practitioners are not yet familiar with it and thus are likely to misdiagnose it. The purpose of this book is to raise awareness of this disease and its diagnostic pitfalls. A wealth of radiological and histopathological images helps clinicians to understand its characteristics in various organs as well as their clinical and basic medical backgrounds. All of the authors are experts who have published numerous important papers in the field. This book will be useful to physicians in various disciplines such as gastroenterology, rheumatology, ophthalmology, otolaryngology, urology, hematology, and respiratory medicine, not only as a textbook but as an authoritative and comprehensive reference work as well.

First book on IgG4-related disease Numerous, detailed radiological and histopathological images An authoritative and comprehensive book written by experts in the field

Autorentext
John H. Stone, MD, MPH is Clinical Director of Rheumatology, Harvard Medical School, Boston, MA, USA and the Chairman of the International Network for the Study of the Systemic Vasculitides (INSSYS). Dr Stone's research interests relate to translational investigations in systemic vasculitis. He has directed two multicenter clinical trials in Wegener's granulomatosis and antineutrophil cytoplasmic antibody-associated vasculitis, the Wegener's Granulomatosis Etanercept Trial (WGET) and the Rituximab in ANCA-associated Vasculitis (RAVE) trial. His other research efforts relate to the identification of new biomarkers through proteomic approaches, and to the development of clinical trials' outcome measures in rheumatic autoimmune diseases

Inhalt

Part I. General remarks.- Chapter 1 An overview.- Chapter 2 Some recollections of the history of research on IgG4-RD.- Chapter 3 History: Pancreas.- Chapter 4 History: Lacrimal and salivary glands.- Chapter 5 Salivary gland lesions in Mikulicz's disease and Küttner's tumor.- Chapter 6 Comprehensive diagnostic criteria for IgG4-RD.- Chapter 7 Autoimmune Pancreatitis with Normal Serum IgG4 Concentrations: What is the correct classification for such patients?.- Chapter 8 Pharmacotherapy of IgG4-related disease.- Chapter 9 B Cell Depletion in IgG4-Related Disease.- Chapter 10 Autoimmune pancreatitis.- Chapter 11 Bile duct lesions.- Chapter 12 Ophthalmology.- Chapter 13 Salivary glands in Mikulicz's disease.- Chapter 14 Lung lesions.- Chapter 15 Kidney and urinary tract lesions.- Chapter 16 Periarterial lesions.- Chapter 17 Other organs (central nervous system, prostate.- Chapter 18 Nerve lesions.- Chapter 19 Scintigraphy and single-photon emission computed tomography.- Chapter 20 Positron Emission Tomography with F-18 fluorodeoxyglucose.- Part III. Pathology.- Chapter 21 Pancreas.- Chapter 22 Sclerosing cholangitis.- Chapter 23 Lacrimal gland and salivary gland lesions.- Chapter 24 Pathological findings of IgG4-related lung disease.- Chapter 25 IgG4-related kidney disease.- Chapter 26 Retroperitoneal fibrosis and arterial lesions.- Chapter 27 Lymph node lesions.- Chapter 28 Skin lesions.- Chapter 29 IgG4-related hepatopathy.- Part IV. Lesson from cases.- Chapter 30 A case of IgG4-related kidney disease first detected because of severe renal dysfunction.- Chapter 31 IgG4-related disease and malignant tumors.- Chapter 32 Membranous nephropathy showing IgG4 deposition in glomerular basement membrane complicating pancreatic, hepatic, and lymph node lesions.- Chapter 33 IgG4-related kidney disease with retroperitoneal fibrosis in a patient with diabetes mellitus.