Functional Imaging and Modeling of the Heart

Therecentdevelopmentsindynamiccardiacimagingandmodelingarethe- sultofanincreasinglyfruitfulcooperationbetweentheoreticians,engineers,and practitioners. Thestandardclinicalparametersareprogressivelybene?ttingfrom moreaccuratequantitativemeasurementsthankstoasimultaneoususeof- phisticateddataacquisitiontechniquessuchasmultichannelECGandMEG, dynamicUS,doppler,X-Ray,CT,helicalCT,MRI,fMRI,SPECT,PET. . . data andadvancedphysicalandmathematicaltools. Itisbecomingpossibleto- cientlycombineprioranatomicalandfunctionalknowledgewithadvanced3D spatio-temporaldigitaldata. Thechallengenowisclearlytocorrelatethemicro structureandfunctionoftheorganfromthecellularlevelwithitsmacroscopic functionalbehavior. TheFIMH2001internationalworkshopaimedtopromotecollaborationb- weenscientistsinsignalandimageprocessing,appliedmathematicsandphysics, biomedicalengineeringandcomputerscience,andexpertsincardiology,rad- logy,biology,andphysiology. TheFIMH2001workshop,inits?rstyear,focused oncomplexheartmodelsinvolvinganatomicalandfunctionalinformation. The goalistograduallymovetowardhybrid3Dbiomechanicalandelectrophysio- gicalmodelsabletosimulatethedynamicbehavioroftheheart. WefeelthatFIMH2001presentedanopportunitytocreateacardio-vascular researchnetworkataEuropeanleveltofederatethemainpluridisciplinary groupsinvolvedinadvancedresearchincardiovascularimagingandmodeling inEurope. Theideaistocreatewhatcouldbecalledthe EuropeanBeating HeartProject . Thepurposeofsuchaprojectistojoinresearche?ortsto- provediagnosisandtherapyofpathologicaldysfunctionsoftheheart,forthe bene?tofthepatient,throughfundamentalandclinicalresearch. September2001 ToivoKatila IsabelleE. Magnin VI Preface Acknowledgements Themembersoftheprogramcommitteedeservespecialthanksfortheirjob inreviewingallthepapers,andfortheirsupportintheorganizationofthe conference. WethankthemembersoftheCREATISunitinLyonandtheLaboratory ofBiomedicalEngineeringinHelsinkifortheirinvolvementandsupportinthe organizationofthisconference. Conferencesupportedby InstitutNationaldesSciencesAppliqu eesdeLyon(INSA),France HelsinkiUniversityofTechnology(HUT),Finland CentreNationaldelaRechercheScienti?que(CNRS),France ScienceAcademyofFinland Jointincentiveaction BeatingHeart oftheCNRS,France FrenchCulturalCenter,Helsinki French-FinnishAssociationforScienti?candTechnicalResearch(AFFRST) FrenchBiomedicalEngineeringSociety(SFGBM) Organization FIMH2001wasco-organizedbytheCREATISLaboratory,CNRSUMR5515, Lyon,France,andtheLaboratoryofBiomedicalEngineeringattheHelsinski UniversityofTechnology,Finland. ConferenceChairs ToivoKatila LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland IsabelleE. Magnin CREATIS,CNRSUMR5515,Lyon,France OrganizationCommittee PatrickClarysse CREATIS,CNRSUMR5515,Lyon,France JohanMontagnat CREATIS,CNRSUMR5515,Lyon,France JukkaNenonen LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland ProgramCommittee T. Arts UniversityofTechnologyofEindhoven,The Netherlands N. Ayache INRIASophia-Antipolis,France S. Baillet LaPiti eSalp etriere,Paris,France M. Barlaud I3S,Sophia-Antipolis,France L. Bidaut H opitauxUniversitairesdeGeneve,Switz- land B. Bijnens MIC,KatholiekeUniversiteitLeuven,Belgium I. Bloch ENST,Paris,France E. Canet CREATIS,Lyon,France P. Clarysse CREATIS,Lyon,France L. Cohen CEREMADE,Paris,France P. Croisille CREATIS,Lyon,France J. Declerck OMIA,Oxford,UnitedKingdom H. Delingette INRIASophia-Antipolis,France J. D hooge MIC,KatholiekeUniversiteitLeuven,Belgium R. Fenici CatholicUniversityofRome,Italy D. Friboulet CREATIS,Lyon,France A. Herment INSERMU494,Paris,France M. Horacek DalhousieUniversity,Canada M. Janier CREATIS,Lyon,France H. Larson HvidovreHospital,Denmark K. Lauerma HelsinkiUniversityCentralHospital,Finland VIII Organization ProgramCommittee(continuation) S. Loncaric UniversityofZagreb,Croatia J. L otj onen VTTTechnology,Tampere,Finland I. E. Magnin CREATIS,Lyon,France M. M akij arvi HelsinkiUniversityCentralHospital,Helsinki, Finland J. Meunier Un

Includes supplementary material: sn.pub/extras

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inreviewingallthepapers,andfortheirsupportintheorganizationofthe conference. WethankthemembersoftheCREATISunitinLyonandtheLaboratory ofBiomedicalEngineeringinHelsinkifortheirinvolvementandsupportinthe organizationofthisconference. Conferencesupportedby InstitutNationaldesSciencesAppliqüeesdeLyon(INSA),France HelsinkiUniversityofTechnology(HUT),Finland CentreNationaldelaRechercheScienti?que(CNRS),France ScienceAcademyofFinland Jointincentiveaction BeatingHeart oftheCNRS,France FrenchCulturalCenter,Helsinki French-FinnishAssociationforScienti?candTechnicalResearch(AFFRST) FrenchBiomedicalEngineeringSociety(SFGBM) Organization FIMH2001wasco-organizedbytheCREATISLaboratory,CNRSUMR5515, Lyon,France,andtheLaboratoryofBiomedicalEngineeringattheHelsinski UniversityofTechnology,Finland. ConferenceChairs ToivoKatila LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland IsabelleE. Magnin CREATIS,CNRSUMR5515,Lyon,France OrganizationCommittee PatrickClarysse CREATIS,CNRSUMR5515,Lyon,France JohanMontagnat CREATIS,CNRSUMR5515,Lyon,France JukkaNenonen LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland ProgramCommittee T. Arts UniversityofTechnologyofEindhoven,The Netherlands N. Ayache INRIASophia-Antipolis,France S. Baillet LaPiti eSalp etriere,Paris,France M. Barlaud I3S,Sophia-Antipolis,France L. Bidaut H opitauxUniversitairesdeGeneve,Switz- land B. Bijnens MIC,KatholiekeUniversiteitLeuven,Belgium I. Bloch ENST,Paris,France E. Canet CREATIS,Lyon,France P. Clarysse CREATIS,Lyon,France L. Cohen CEREMADE,Paris,France P. Croisille CREATIS,Lyon,France J. Declerck OMIA,Oxford,UnitedKingdom H. Delingette INRIASophia-Antipolis,France J. D hooge MIC,KatholiekeUniversiteitLeuven,Belgium R. Fenici CatholicUniversityofRome,Italy D. Friboulet CREATIS,Lyon,France A. Herment INSERMU494,Paris,France M. Horacek DalhousieUniversity,Canada M. Janier CREATIS,Lyon,France H. Larson HvidovreHospital,Denmark K. Lauerma HelsinkiUniversityCentralHospita

Inhalt
Invited Speaker.- Modules in Cardiac Modeling: Mechanics, Circulation, and Depolarization Wave.- Anatomical Modeling.- Geometrical Modeling of the Heart and Its Main Vessels.- Reconstructing 3D Boundary Element Heart Models from 2D Biplane Fluoroscopy.- Introducing Spectral Estimation for Boundary Detection in Echographic Radiofrequency Images.- Geometrical Modelling of the Fibre Organization in the Human Left Ventricle.- Invited Speaker.- Challenges in Modelling Human Heart's Total Excitation.- Motion and Deformation.- Two-Dimensional Ultrasonic Strain Rate Measurement of the Human Heart in Vivo.- Deformation Field Estimation for the Cardiac Wall Using Doppler Tissue Imaging.- A New Kinetic Modeling Scheme for the Human Left Ventricle Wall Motion with MR-Tagging Imaging.- Integrated Quantitative Analysis of Tagged Magnetic Resonance Images.- Invited Speaker.- Measurement of Ventricular Wall Motion, Epicardial Electrical Mapping, and Myocardial Fiber Angles in the Same Heart.- Functional Imaging.- A 3-D Model-Based Approach for the PET-Functional and MR-Anatomical Cardiac Imaging Data Fusion.- 3D Regularisation and Segmentation of Factor Volumes to Process PET H2 15O Myocardial Perfusion Studies.- In Vivo Assessment of Rat Hearts with and without Myocardial Infarction by Cine NMR - Comparison of the NMR Method to Invasive Techniques and Application to Intervention Studies.- Dempster Shafer Approach for High Level Data Fusion Applied to the Assessment of Myocardial Viability.- Invited Speaker.- Experimental and Computational Modeling of Cardiac Electromechanical Coupling.- Towards Electromechanical Modeling.- Towards Model-Based Estimation of the Cardiac Electro-Mechanical Activity from ECG Signals and Ultrasound Images.- A Physiologically-Based Model for the ActiveCardiac Muscle Contraction.- Post-Systolic Thickening in Ischaemic Myocardium: A Simple Mathematical Model for Simulati…