Comprehensively and systematically introduces the design principles, response mechanisms, and imaging applications of organic small-molecule fluorescence probes.

Autorentext

Professor Caixia Yin is a Director of the Key Laboratory of Chemical Biology and Molecular Engineering at the Ministry of Education and Institute of Molecular Science, Shanxi University, China. She received the Outstanding Young Scholar award from the National Natural Science Foundation of China for and was selected as the 2022 Elsevier China Highly Cited Scholar, the 2022 the World's Top 2% Top Scientists (Lifetime Lists), and the 2020 Chinese Chemical Letters Outstanding Young Scholar.

Inhalt
1 FLUORESCENCE AND MOLECULAR RECOGNITION
1.1 Advancing fluorescence theory
1.2 Advancing fluorescent dyes
1.3 Fluorescent probes for molecular recognition

2 FLUORESCENT PROBES
2.1 Excitation modes of fluorescent probes
2.2 Fluorescence reporting mode
2.3 Optical modulation mechanism of fluorescent probes
2.4 The reaction mechanism of small molecule fluorescent probes

3 FLUORESCENCE PROBE OF REACTIVE OXYGEN SPECIES (ROS)
3.1 Fluorescence probe of hydrogen peroxide (H2O2)
3.2 Fluorescence probe of hypochlorous acid (HClO)
3.3 Fluorescence probe of hydroxyl radical (·OH)
3.4 Fluorescence probe of superoxide anion(O2?-)
3.5 Fluorescence probe of Singlet oxygen (1O2)

4 FLUORESCENCE PROBE OF REACTIVE SULFUR SPECIES (RSS)
4.1 Introduction to biological functions of RSS
4.2 Synthesis, recognition mechanism, and biomedical applications of Cys probes
4.3 Synthesis, recognition mechanism and application of Hcy probes
4.4 Synthesis,recognition mechansim and biomaging of GSH probes
4.5 Synthesis,recognition mechansim and biomaging of H2S probes
4.6 Synthesis,recognition mechansim and biomaging of SO2 probes
4.7 Synthesis, recognition mechansim and biomaging of polysulfide probes

5 FLUORESCENT PROBES FOR REACTIVE NITROGEN SPECIES
5.1 Introduction to biological functions of RNS
5.2 Synthesis, recognition mechanism and bioapplication of NO probes
5.3 Synthesis, recognition mechanism and bioapplication of ONOO- probes
5.4 Synthesis, recognition mechanism and bioapplication of HNO

6 FLUORESCENT PROBES FOR REACTIVE CARBON SPECIES
6.1 Introduction to biological functions of RCS
6.2 Synthesis, recognition mechanism, and bioimaging of carbon monoxide probes
6.3 Synthesis, recognition mechanism, and bioapplication of formaldehyde
6.4 Synthesis, recognition mechanism, and bioapplication of ethylene
6.5 Synthesis, recognition mechanism, and bioimaging of malonaldehyde probes

7 FLUORESCENT PROBES FOR OXIDOREDUCTASE ENZYMES
7.1 Brief introduction of enzymes in redox modulation
7.2 Synthesis, recognition mechanism and application of monoamine probes
7.3 Synthesis, recognition mechanism and application of NAD(P)H: quinine oxidoreductase probes
7.4. Synthesis, recognition mechanism and application of Nitroreductase probes
7.5 Synthesis, recognition mechanism and application of tyrosinase probes
7.6 Synthesis, recognition mechanism and application of thioredoxin reductase probes

8 FLUORESCENT PROBES FOR NEUROTRANSMITTERS
8.1 Biological function of neurotransmitter
8.2 Synthesis, recognition mechanism, and bioimaging of norepinephrine probes
8.3 Synthesis, recognition mechanism, and bioimaging of dopamine probes
8.4 Synthesis, recognition mechanism, and bioimaging of acetylcholine probes
8.5 Synthesis, recognition mechanism, and bioimaging of glutamic acid
8.6 Synthesis, recognition mechanism, and bioimaging of 5-hydroxytryptamine
8.7 Synthesis, recognition mechanism, and bioimaging of histamine
8.8 Other neurotransmitters

9 DUAL-RESPONSE FLUORESCENT PROBES FOR THE ABOVE REACTIVE SPECIES
9.1 Synthesis, recognition mechanism, and biological imaging of RSS dual responsive fluorescent probes
9.2 Synthesis, recognition mechanism and bioimaging of ROS double-response fluorescent probes
9.3 Synthesis, recognition mechanism, and biological imaging of RSS and ROS dual responsive fluorescent probes
9.4 Synthesis, recognition mechanism, and bioimaging of dual-responsive fluorescent probes for RSS and RNS
9.5 Synthesis, recognition mechanism, and bioimaging of active molecule and enzyme dual-responsive fluorescent probes
9.6 Synthesis, recognition mechanism, and bioimaging of active species with ATP-dual-responsive fluorescent probes

10 OTHER BIOACTIVE SPECIES FLUORESCENT PROBES
10.1 Synthesis, recognition mechanism, and bioimaging of NAD(P)H
10.2 Synthesis, recognition mechanism and bioimaging of pyruvic acid probes
10.3 Synthesis, recognition mechanism and bioimaging of Lactic acid probes
10.4 Synthesis, recognition mechanism, and bioimaging of lipid peroxidation probes
10.5 Synthesis, recognition mechanism, and bioimaging of ATP

11 SUMMARY