Endoplasmic Reticulum

In step with the surge of interest in the endoplasmic reticulum, the current volume takes an integrated look at this functionally diverse organelle. Coverage includes protein translocation and export, lipid metabolism, antigen presentation, and many other subjects, gleaned from such diverse fields as cell biology, enzymology and membrane biochemistry, immunology, and signal transduction.

Inhalt
1 Mechanisms of Translocation of Proteins across Membranes.- 2 Components and Mechanisms Involved in Transport of Proteins into the Endoplasmic Reticulum.- 3 Folding, Assembly, and Posttranslational Modification of Proteins within the Lumen of the Endoplasmic Reticulum.- 4 Biological Functions and Biosynthesis of Glycolipid-Anchored Membrane Proteins.- 5 Membrane Cycling between the ER and Golgi Apparatus and Its Role in the Regulation of Biosynthetic Transport.- 6 The Intermediate Compartment between Endoplasmic Reticulum and Golgi Complex in Mammalian Cells.- 7 The Endoplasmic Reticulum as a Site of Protein Degradation.- 8 The Endoplasmic Reticulum Is the Site of Lipoprotein Assembly and Regulation of Secretion.- 9 Endoplasmic Reticulum and the Control of Ca2+ Homeostasis.- 10 Antigen Processing and Presentation: The Role of the Endoplasmic Reticulum.- 11 Distribution, Biosynthesis, and Function of Mevalonate Pathway Lipids.- 12 Phospholipid Translocation in the Endoplasmic Reticulum.- 13 Cytochrome P-450 in the Endoplasmic Reticulum: Biosynthesis, Distribution, Induction, and Degradation.- 14 NADH-Cytochrome b5 Reductase and Cytochrome b5: The Problem of Posttranslational Targeting to the Endoplasmic Reticulum.- 15 Motility and Construction of the Endoplasmic Reticulum in Living Cells.