Digestive System

During the years that have intervened since the third volume of the International Life Sciences Institute (ILSI) Monographs on Pathology of Laboratory Animals, Digestive System, was published, new information of interest to pathologists has developed at a rather remarkable pace. Standardized nomenclature has been proposed and gained significant acceptance during the period since the first edition and is being utilized on an international basis. This has resulted in improvement in communi cation of pathologic data to regulatory agencies and in scientific publica tions worldwide. This monograph series and others sponsored by ILSI have had significant effects on improved communications and the inter national acceptance of standardized nomenclature. In this second edition, new formats have been used in some instances where more appropriate for the subjects to be covered. The format introduced in the first edition remains useful as it emphasizes the neces sity to recognize the morphologic features of pathologic lesions to iden tify them precisely. This identification is an essential first step toward development of new insights into pathogenetic mechanisms and their use in decisions eventually applicable to public health.

Klappentext

This is the 2nd edition of the third volume in this series. Since the 1st edition, new information has developed at a remarkable pace. Both editions propose standardized nomenclature that is being used internationally, gaining significant acceptance. The result is improved communication of pathologic data to regulatory agencies and in scientific publications worldwide. New information on the nature and variability of preneoplastic lesions in the liver of laboratory rodents is included. The book expands data on the accompanying changes in enzyme activity in affected liver cells. Spongiosis hepatis in the rat and its relation to spongiotic pericytoma are discussed thoroughly. Information on many other pathologic entities is brought up to date, making it an even more useful and expanded reference text.

Inhalt
The Liver.- Neoplasms.- Foci of Altered Hepatocytes, Rat.- Foci of Altered Hepatocytes, Mouse.- Hepatocellular Adenoma, Liver, Rat.- Hepatocellular Carcinoma, Liver, Rat.- Cholangiofibroma and Cholangiocarcinoma, Liver, Rat.- Cholangioma, Liver, Rat.- Hemangiosarcoma, Liver, Rat.- Hemangioma, Liver, Rat.- Hepatoblastoma, Mouse.- Kupffer's Cell Sarcoma, Liver, Rat.- Spongiosis Hepatis and Spongiotic Pericytoma, Rat.- Focal Carcinoma in Hepatocellular Adenoma, Liver, Mouse.- Hyperplasia, Adenoma, Gallbladder, Hamster.- Mesothelioma, Peritoneum, Induced by Mineral Fibers, Rat.- Non-neoplastic Lesions.- Polyploidy, Liver, Rat.- Intranuclear and Intracytoplasmic Inclusions, Liver, Rat.- Extramedullar Hematopoiesis, Liver, Rat.- Nutritional Fatty Liver, Cirrhosis, and Hepatocellular Carcinoma, Rat, Mouse.- Cirrhosis, Mouse.- Peliosis Hepatis, Rodents.- Hyperplasia, Diffuse, Following Partial Hepatectomy, Mouse.- Oval Cells in Rodent Liver, Mouse, Rat.- Herniation of Liver Through Esophageal Hiatus, Rat.- Viral Infections.- K Virus Infection, Mouse.- Mouse Hepatitis Virus Infection, Liver, Mouse.- Rat Parvovirus Infection, Liver.- Mousepox, Liver, Mouse.- Reovirus Type 3 Infection, Liver, Mouse.- Bacterial Infections.- Tyzzer's Disease in the Rat, Mouse, and Hamster.- Corynebacterium kutscheri Infection, Liver, Mouse and Rat.- Idiopathic Focal Hepatic Necrosis in Inbred Mice.- Multifocal Inflammation, Liver, Rat.- The Salivary Glands.- Histology and Ultrastructure, Salivary Glands, Mouse.- Neoplasms.- Myoepithelioma, Salivary Glands, Mouse.- Adenoma, Adenocarcinoma, Salivary Gland, Mouse.- Polyoma Virus Infection, Salivary Glands, Mouse.- Non-neoplastic Lesions.- Cytomegalovirus Infection, Salivary Glands, Mouse, Rat, and Hamster.- Sialodacryoadenitis (SDA) VirusInfection, Rat.- The Exocrine Pancreas.- Embryology, Histology, and Ultrastructure of the Exocrine Pancreas.- Neoplasms.- Acinar Cell Carcinoma, Pancreas, Rat.- Experimental Carcinogenesis, Exocrine Pancreas, Hamster and Rat.- Non-neoplastic Lesions.- Atrophy, Exocrine Pancreas, Rat.- Exocrine Pancreas of Hypophysectomized Rats.- Necrotizing Pancreatitis Induced by 4-Hydroxyaminoquinoline, Rat.- The Oral Cavity.- Squamous Cell Carcinoma, Tongue, Rat.- The Esophagus.- Neoplasms.- Squamous Cell Papilloma, Esophagus, Rat.- Carcinoma In Situ, Esophagus, Rat.- Squamous Cell Carcinoma, Esophagus, Rat.- Papillary and Nonpapillary Squamous Cell Carcinoma, Esophagus, Rat (Zinc Deficiency, Alcohol, and Methylbenzylnitrosamine).- Adenocarcinoma, Esophagus, Rat.- Adenosquamous Carcinoma, Esophagus, Rat.- The Stomach.- Anatomy, Histology, Ultrastructure, Stomach, Rat.- Neoplasms.- Papilloma, Forestomach, Rat.- Squamous Cell Carcinoma Forestomach, Rat.- Adenoma, Glandular Stomach, Rat.- Adenocarcinoma, Glandular Stomach, Rat.- Leiomyoma and Leiomyosarcoma, Stomach, Rat.- The Small Intestines.- Viral Infections.- Mouse Hepatitis Virus Infection, Intestine, Mouse.- Murine Rotavirus Infection, Intestine, Mouse.- Adenovirus Infection, Intestine, Mouse, Rat.- Infectious Diarrhea of Infant Rats (Rotavirus).- Bacterial Infections.- Clostridial Enteropathies, Hamster.- Citrobacter freundii Infection, Colon, Mouse.- Proliferative Ileitis, Hamster.- Streptococcal Enteropathy, Intestine, Rat.- Helminth and Protozoal Infections.- Spironucleus muris Infection, Intestine, Mouse, Rat, and Hamster.- Giardia muris Infection, Intestine, Mouse, Rat, and Hamster.- The Large Intestine.- Bacterial Infection.- Coliform Typhlocolitis, Immunodeficient Mice.- Neoplasms.- Adenocarcinoma, Colon and Rectum, Rat.