Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.

Explores obvious analogies and profound differences between cancer and pregnancy Fills the gap and provides a balance and hopeful view on the value of rigorous investigation of pregnancy for understanding biology, developing diagnostics and possibly developing new treatment modalities Provides an in-depth discussion of the clinical and basic features of pregnancy and cancer

Klappentext

Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.

Inhalt
I: Clinical Aspects: Diagnosis and Management.- 1 The Epidemiology of Cancer in Pregnancy.- 2 Placental and Fetal Cancers.- 3 Breast Cancer and Pregnancy.- 4 Gynaecologic Malignancies in Pregnancy.- 5 Hematologic Malignancies in Pregnancy.- 6 Melanoma in Pregnancy.- 7 Rare Tumours in Pregnancy.- 8 Colorectal Cancer in Pregnancy.- 9 Radiologic Diagnosis of Cancer in Pregnancy.- 10 Pregnancy Derived Tumor Marker.- 11 Chemo and Radiation Therapy During Pregnancy.- 12 Management of Cancer in Pregnancy (Case Reports).- 13 Transplacental Carcinogenesis: Role of Chemicals, Radiation and Viruses.- II Comparative Aspects of Pregnancy Development and Tumour Biology.- 14 Metabolism of Chemotherapeutic Drugs by Maternal and Conceptus Tissues.- 15 Adverse Reproductive Outcome Potential of Cancer Therapies During Pregnancy.- 16 Immunomodulatory Analogies Between Trophoblastic and Cancer Cells and Their Hosts.- 17 Protective Role of Human Chorionic Gonadotrophin and Luteinizing Hormone Against Breast Cancer.- 18 Proliferation, Differentiation and Apoptosis in Pregnancy and Cancer.- 19 Controlled vs Uncontrolled Angiogenesis: Color Doppler Studies.- 20 Angiogenesis and Vasculogenesis in Pregnancy and in Tumor Development.- 21 Trophoblast Implantation Versus Tumor Invasion.- 22 Pregnancy Derived Compounds that Control Proliferation.- 23 Cancer and Pregnancy: Bioethical and Legal Dilemmas.- Epilogue Cancer and Pregnancy: a Reason for Hope.