Calcium Homeostasis

Volume III of this series deals with cellular calcium homeostasis aspects and structural properties of extra- and intracellular calcium-binding proteins are described. The structure/function relationship of calcium-transport proteins, and the role of calcium as a regulator of the activity specific protein kinases and phosphatase(s) are also described. The volume is a valuable source of information for graduate students and researchers who want to acquaint themselves with various aspects extracellular calcium. .

The companion book series to the "Journal of Biological Inorganic Chemistry" Includes supplementary material: sn.pub/extras

Klappentext

This new "Topics" series is an "offspring" of our well established series "Structure and Bonding". The foundation of TBIC reflects the importance research has gained at the interface of inorganic and biological chemistry in the past years.BR Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of high current interest written by leading international experts.

Inhalt
Calcium Homeostasis and Its Evolution.- Evolution of EF-Hand Proteins.- Calmodulin Target Recognition: Common Mechanism and Structural Diversity.- Calcium-Binding EGF-like Domains.- Calmodulin-Dependent Protein Kinases.- Structure of Calcineurin and Its Complex with Immunophilins.- The Ca2+ Pump of Sarcoplasmic and Endoplasmic Reticulum Membranes.- The Plasma Membrane Ca2+ ATPase.- The Na+/Ca2+ Exchanger: Structural Aspects, Function and Regulation.