In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In Biomedical Informatics, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful Methods in Molecular Biology™ series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Wide-ranging and innovative, Biomedical Informatics is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers.

Features cutting-edge methods for information and knowledge discovery in bio-medical research Includes modern methods of software design and software engineering in the area of bio- and neuro- informatics Provides descriptions of modern architectures for the development of scientific cyber infrastructures

Inhalt
Management of Information in Distributed Biomedical Collaboratories.- Enabling Public Data Sharing: Encouraging Scientific Discovery and Education.- Mediator Infrastructure for Information Integration and Semantic Data Integration Environment for Biomedical Research.- System Biology of Gene Regulation.- Current Computational Methods for Prioritizing Candidate Regulatory Polymorphisms.- Methods of Information Geometry in Computational System Biology (Consistency between Chemical and Biological Evolution).- Protein Structure Prediction Based on Sequence Similarity.- Applications of Bioinformatics to Protein Structures: How Protein Structure and Bioinformatics Overlap.- Knowledge Discovery via Machine Learning for Neurodegenerative Disease Researchers.- Brain Model of Text Animation as a Data Mining Strategy.- Processes Parallel Execution Using Grid Wizard Enterprise.- Single Sign-On in a Grid Portal.