Exciting new "biologic" therapies for treating leukemia are appearing so rapidly that clinicians often find it difficult to make informed decisions about their use when making patient treatment decisions. Biologic Therapy of Leukemia summarizes and reviews all the available data concerning these cutting-edge biologic therapies so that practicing clinicians can make the correct patient-care choices. Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.

Includes supplementary material: sn.pub/extras

Zusammenfassung
Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.

Inhalt
I: Immunotherapy.- 1 Human Leukemia-Derived Dendritic Cells as Tools for Therapy.- 2 The Graft vs Leukemia Effect.- 3 Unconjugated Monoclonal Antibodies.- 4 Drug Immunoconjugate Therapy of Acute Myeloid Leukemia.- 5 Radiolabeled Monoclonal Antibodies.- II: Cytokines.- 6 Interferons.- 7 Interleukin-2 Treatment of Acute Leukemia.- III: Targeted Therapeutics.- 8 Antisense Therapy.- 9 Signal Transduction Inhibitors.- 10 P-Glycoprotein Inhibition in Acute Myeloid Leukemia.- 11 Targeting the Apoptotic Machinery as a Potential Antileukemic Strategy.- IV: Differentiation Agents.- 12 Arsenicals: Past, Present, and Future.- 13 All-Trans-Retinoic Acid in the Treatment of Acute Promyelocytic Leukemia.- V: Gene Therapy.- 14 Gene Therapy.