Exposure of patients to a high oxygen environment is a standard treatment in a select group of patients. The development of oxygen toxicity must be avoided in those patients. This book describes the effects of normobaric and hyperbaric oxygen treatment of animal models on brain biochemical and physiological responses. This book provides a summary of our knowledge on the effects of hyperbaric oxygenation on mitochondrial activity in vivo, and other functions of the brain. A chapter covering the use of hyperbaric hyperoxia in patients' brain pathology and care is also included. This is an ideal book for students, research groups, and clinicians studying hyperbaric oxygen and its connection to mitochondrial activity and brain physiological functions.

Aids clinicians and scientists in directing their future clinical and experimental use Describes direct real time monitoring of brain functions including mitochondrial function Presents information on the interaction between hyperbaric oxygenation

Autorentext

Prof. Avraham Mayevsky is a Professor Emeritus in The Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel.

Prof. Avraham Mayevsky's field of research since he started his Post-Doc training with Prof. Britton Chance in 1972, was Energy metabolism, including mitochondrial function in vivo, of the brain mainly and other tissues In Vivo, exposed to various pathophysiological conditions. During the 50 years of activity he was able to accomplish a large number of goals that have a very significant impact on the understanding of pathophysiological processes in the brain and other organs evaluated under In Vivo conditions. His vision was to develop experimental approaches and tools that will enable him to study various physiological processes in experimental animals and at the same time, will be ready for clinical applications.

Inhalt

Chapter 1-Introduction and Historical Background.- Chapter 2-Basic Concepts of Brain Monitoring Systems.- Chapter 3-Scientific Background to Hyperbaric Oxygenation(HBO).- Chapter 4-Typical Brain Mitochondrial Responses to Hyperbaric Oxygenation.- Chapter 5-Effect of the Pressure Level on the Oxygen Toxicity Process.- Chapter 6-Responses to Oxygen Toxicity after Various Treatments.- Chapter 7-Interaction between Carbon Monoxide(CO) and Hyperbaric Oxygenation.- Chapter 8-Effects of Age on the Responses to Hyperbaric Hyperoxia.- Chapter 9-Brain Multiparametric Responses to Hyperbaric Hyperoxia.- Chapter 10-Effects of Age on the Responses to Hyperbaric Hyperoxia.- Chapter 11-Hyperbaric Hyperoxia in Patients After Chest Injury or Ischemic Stroke.- Chapter 12-Discussion and Conclusions. <p