A Brief History of Blood and Lymphatic Vessels

Most complete history of our understanding of angiogenesis and vascular biology today
First conceptual and philosophical analysis in the field
In dept discussion of our current understanding of angiogenesis and vasculature

Autorentext
Andreas Bikfalvi

University of Bordeaux and National Institute of Health and Medical Research (INSERM)

Angiogenesis and Tumor Microenvironment Laboratory (LAMC - INSERM U1029)

Pessac, France

Inhalt
The vasculature, what is it?.- Historical consideration.- The vasculature in evolution.- Where it all began.- Culture of vascular cells in vitro.- The discovery of the first stimulating factors of blood vessels.- Vascular Endothelial growth factor (VEGF) : the cornerstone of angiogenesis stimulators.- Inhibition of angiogenesis "successes and deceptions".- Stimulating angiogenesis.- The story is more complicated than anticipated.- How to study angiogenesis.- Lymphangiogenesis joins in.- Endothelial progenitors and stem cells.- The neuronal connection.- Vascular targeting and vessel destruction ("Vascular targeting").- What future for angiogenesis?.- Philosophical aspect of the vascular tree.- Concluding remarks.