Adipose Tissue and Adipokines in Health and Disease

The aim of Adipose Tissue and Adipokines in Health and Disease is to provide comprehensive information regarding adipose tissue, its physiological functions and its role in disease. This volume contains a collection of information spanning the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical aspects, in one place. This book is indispensable for basic researchers and clinicians interested in the fields of obesity, metabolic diseases, inflammation and immunity, and specialists in each of the pathologies associated with obesity.

Provides a comprehensive review of fundamental adipose tissue anatomy and physiology Introduces a novel and dynamic model for adipose tissue study Examines vasoactive and inflammatory molecules produced by adipose tissue Describes the role of macrophages in obesity and metabolism Discusses the interaction between adipocytes and hematopoietic cells in bone marrow Analyzes the metabolic disturbances associated with disorders of adipose tissue development and distribution

Inhalt
Adipose Tissue: Structure and Function.- The Adipose Organ.- Metabolism of White Adipose Tissue.- Leptin.- Adiponectin.- Adipokines as Regulators of Immunity and Inflammation.- Vasoactive Factors and Inflammatory Mediators Produced in Adipose Tissue.- Regulation of the Immune Response by Leptin.- Leptin in Autoimmune Diseases.- Leptin and Gastrointestinal Inflammation.- Adiponectin and Inflammation.- Interactions Between Adipocytes and Immune Cells.- Macrophages, Adipocytes, and Obesity.- Interactions of Adipose and Lymphoid Tissues.- Adipose Tissue and Mast Cells.- Bone Marrow Adipose Tissue.- Weight Gain and Weight Loss.- The Epidemiology of Obesity.- Environmental Aspects of Obesity.- Developmental Perspectives on the Origins of Obesity.- Genetics of Obesity.- Inherited and Acquired Lipodystrophies.- Mechanisms of Cachexia.- Effect of Weight Loss on Disease.- Adipose Tissue and Disease.- Adipose Tissue and Insulin Resistance.- Adipokines in Non-Alcoholic Fatty Liver Disease.- Adiposity and Cancer.- Obesity and the Heart.- Obesity and Asthma.- Adiposity and Kidney Disease.- Obesity and Joint Disease.