Autorentext

Prof. (Dr.) Abhishek Tiwari works as Professor and Head, Amity Institute of Pharmacy, Amity University, Lucknow Campus, Uttar Pradesh, India. He completed his BPharm. from Jiwaji University, Gwalior, in 2006; MPharm. from M. S. Ramaiah College of Pharmacy, Bangalore, in 2009; and Ph.D. from Uttarakhand Technical University, Dehradun, in 2015. He has than 16 years of teaching and research experience. Dr Tiwari has received more than 110 lakhs Indian rupees in grants from various funding agencies. Dr. Tiwari is a distinguished academic and researcher with a prolific record of innovation and scholarship. He has been granted 43 patents and has numerous additional patents currently under review. With over 85 research papers published in national and international journals, Dr. Tiwari has significantly contributed to his field. He is the author of more than 31 Indian and international books and has contributed to 68 book chapters. Dr. Tiwari has successfully supervised two PhD candidates and is a recognized research supervisor at Amity University Uttar Pradesh, Lucknow campus. He serves on the editorial boards of several national and international journals and is a dedicated peer reviewer for leading publishers. His excellence in teaching and research has been recognized with multiple awards, including the Best Researcher Award (2022), Best Author Award (2019), Best Teacher Award (2019), and the Outstanding Teacher Award (2014 and 2015).

Prof. (Dr.) Varsha Tiwari works as Professor and Head, Department of Pharmacognosy, Amity Institute of Pharmacy, Amity University, Lucknow Campus, Uttar Pradesh, India. She completed her Doctorate from Uttarakhand Technical University in 2016, and MPharm from M. S. Ramaiah University, Bengaluru, in 2009. She has more than 16 years of teaching and research experience and has been granted 40 Indian and international patents. In addition, she has submitted a number of patents for approval. She has published 17 books and 65 book chapters and has received more than 98 lakhs Indian rupees in grants from various funding agencies. She has published more than 80 research papers and has guided close to a hundred doctoral, postgraduate, and graduate students. She has organized many conferences and delivered many invited lectures at conferences. She has also received Young Scientist Award, Young Author Award, and Pharmacy Recognition Award at the National level.

Klappentext

Exploring the Synthesis, Ethnopharmacology, and Therapeutic Applications of Bioactive Polyphenols offers a comprehensive examination of one of the most dynamic areas in natural product chemistry and drug discovery. Polyphenols, long recognized for their diverse biological activities, are now at the forefront of research in preventive medicine, nutraceuticals, and pharmaceutical innovation. This book brings together the chemistry, traditional uses, and modern therapeutic perspectives of bioactive polyphenols in a single, well-structured volume.

The aim of this book is to bridge the gap between traditional ethnopharmacological knowledge and cutting-edge synthetic and therapeutic research. By integrating interdisciplinary perspectives, it provides a unique resource for understanding both the molecular intricacies of polyphenols and their real-world applications in treating chronic diseases. What sets this work apart is its balanced approach offering in-depth scientific analysis while also capturing the cultural and historical significance of these bioactive compounds.

Key Features:

• Detailed coverage of the chemical synthesis and structural diversity of major polyphenols.
• Comprehensive insights into ethnopharmacological practices involving polyphenol-rich plants across different cultures.
• Thorough discussion of therapeutic applications, including cardiovascular, neuroprotective, anticancer, and anti-inflammatory potentials.
• Integration of recent advances in clinical studies and drug formulation strategies.
• This book includes extended chapters on nanotechnology-based delivery systems and sustainability in polyphenol extraction, and updated case studies highlighting translational research. This volume is an essential reference for researchers, academicians, and graduate students in pharmaceutical sciences, medicinal chemistry, pharmacognosy, and natural product research. It will also be invaluable to health-care professionals, nutritionists, and industry specialists seeking to explore the therapeutic promise of polyphenols and their role in future drug discovery.

Inhalt

1. Introduction to Bioactive Polyphenols 2. Synthetic Strategies for Bioactive Polyphenols 3. Synthesis of Phenolic Acid and Flavanoids 4. Total Synthesis of Resveratrol and Stilbenes 5. Synthesis of Lignans and Lignan Glycosides 6. Chemical Modifications of Polyphenols 7. Synthesis of Polyphenol Conjugate and Prodrugs 8. Bioactive Polyphenols in Drug Discovery 9. Applications of Synthetic Bioactive Polyphenols 10. Future directions in Polyphenol synthesis for the treatment of Neuropathic Pain 11. Enzymatic Approaches in Polyphenol Synthesis 12. Multicomponent Reaction for Polyphenol Synthesis 13. Sustainable Synthesis of Bioactive Polyphenols 14. Advances in Polyphenol Modification and Functionalization 15. Nanotechnology for Polyphenol Delivery and Applications 16. Enhancing Polyphenol Bioavailability: Cutting-Edge Advances and Strategies 17. Synthetic Polyphenols for Neurodegenerative Diseases 18. Polyphenols in Functional Materials and Biotechnology 19. Challenges and Opportunities in Polyphenol Synthesis