Numerous examples are known of the application of catalyzed hydrogenation and hydrogenolysis reactions in synthetic organic chemistry. However, catalyst and reaction conditions are often chosen on the analogy of literature data without a good knowledge of the influence of reaction variables and of the structure of the reactant on the various possible modes of reaction. In order to improve such an intuitive procedure it is essential to dispose of an understanding of the reaction mechanisms which are operative in hydrogena tion and hydrogenolysis reactions and which govern i.a. the selectivity of a given pathway with respect to consecutive and parallel reactions. Although organic chemistry and, in particular, hydrogenation and hydro genolysis reactions remain an experimental science this book has been written to give the organic chemist the insight and know-how necessary to apply these reactions successfully to synthetic problems. I warmly recommend it as a book which will enable the organic chemist to rationalize many of the phenomena of catalytic hydrogenation and hydrogenolysis reactions, whereby it surely helps the organic chemist to solve forthcoming synthetic problems in this field. In addition, it seems to me a useful book for physical and physical-organic chemists working in the field of homogeneous and heterogeneous catalysis. Finally, the ten years' experience of both authors in the field of catalysis and synthetic organic chemistry - as reflected by some forty publications guarantees a well-considered review containing many examples directly from the bench.

Inhalt
I. Introduction.- 1. The reactions.- 2. The active site.- 3. Mechanistic investigations.- 4. The catalyst.- 5. The metals.- 6. Reaction conditions.- 7. Apparatus, procedures, and safety precautions.- II. Hydrogenation.- 1. Introduction.- 2. Hydrogenation of alkenic double bonds.- 3. Hydrogenation of aromatic rings.- 4. Semi-hydrogenation of carbon-carbon triple bonds.- 5. Hydrogenation of carbon-oxygen double bonds.- 6. Hydrogenation of carbon-nitrogen multiple bonds.- 7. Enantioselective Hydrogenation.- III. Hydrogenolysis.- 1. Introduction.- 2. Carbon-hydrogen hydrogenolysis (exchange).- 3. Carbon-carbon hydrogenolysis.- 4. Carbon-oxygen hydrogenolysis.- 5. Carbon-nitrogen hydrogenolysis.- 6. Carbon-sulphur hydrogenolysis.- 7. Carbon-halogen hydrogenolysis.- 8. Hydrogenolysis of non-carbon bonds.