This contributed volume reviews the recent progress in our understanding of membrane transport in yeast including both Saccharomyces cerevisiae and non-conventional yeasts. The articles provide a summary of the key transport processes and put these in a systems biology context of cellular regulation, signal reception and homeostasis.

After a general introduction, readers will find review articles covering the mechanisms and regulation of transport for various substrates ranging from diverse nutrients to cations, water and protons. These articles are complemented by a chapter on extremophilic yeast, a chapter on the mathematical modelling of ion transport and two chapters on the role of transport in pathogenic yeasts and antifungal drug resistance. Each article provides both a general overview of the main transport characteristicsof a specific substrate or group of substrates and the unique details that only an expert working in the field is able to transmit to the reader.

Researchers and students of the topic will find this book to be a useful resource for membrane transport in yeast collecting information in one complete volume, which is otherwise scattered across many papers. This might also be interesting for scientists investigating other species in order to compare transport mechanisms with known functions in yeast with the cells on which they work.

Inhalt

Membrane transport in yeast, an introduction.- Cell surface interference with plasma membrane and transport processes in yeasts.- The role of proton transport and pH in yeast transport.- Function and regulation of fungal amino acid transporters: insights from predicted structure.- Water transport in yeasts.- Sugar and Glycerol Transport in Saccharomyces cerevisiae.- The CRaZy calcium cycle.- Potassium and sodium transport in yeast.- Carboxylic acids plasma membrane transporters in Saccharomyces cerevisiae.- Inorganic phosphate and sulfate transport in S. cerevisiae.- Interactions between monovalent cations and nutrient homeostasis.- Mathematical modelling of cation transport and regulation in yeast.- Transport sys tems in halophilic fungi.- Antifungals: Mechanism of Action and Drug Resistance.- Candida Efflux ATPases and Antiporters in Clinical Drug Resistance.