Reviewing current studies and previously unpublished research from leading laboratories around the world, Unravelling Lipid Metabolism With Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. It provides an extensive overview of statistical approaches to microarray data, as well as discussions on how microarrays can be used to understand the role of lipids in the initiation or prevention of disorders such as cancer, diabetes, and obesity. Of particular note is a chapter by the only group known to study the effect of lipids on transcriptomics in multiple brain regions.

Autorentext

Alvin Berger, Matthew A. Roberts

Inhalt

Data Analysis and Statistical Interpretation in Microarray Experiments. Exploring Fatty Acid and Cholesterol Metabolism Using Microarrays. Exploring the Roles of PPARs, HNFs, and SREBPs Using Microarrays. Exploring Lipids and Carcinogenesis Using Microarrays. Exploring How Lipids Affect Insulin Secretion Using Microarrays. Other "Omic" Techniques for Unravelling Lipid Metabolism.