The Massachusetts General Hospital Guide to Depression

This book present the most cutting edge treatment options for patients struggling with depression. Written by experts in this area, the book begins by establishing the general themes that are most critical to accurately diagnosing and effectively treating depression. The text then covers new medication options, new psychotherapy, non-pharmacological treatments, the needs of special populations, and emerging research. Each chapter begins with a case vignette that clearly illustrates key characteristics of the disorder process or treatment before covering the history, research support, and new advances of these areas. In addition, the chapters include a description of how to apply this topic in treatment and frequently asked questions and answers, making this a highly practical guide for any physician working with a depressed patient.

Treatment of Depression is an excellent resource for all clinicians working with depressed patients, including psychiatrists, psychologists, general practitioners, and all others.

Autorentext
Benjamin G. Shapero, Ph.D.
Assistant in Psychology, Department of Psychiatry, Massachusetts General Hospital
Member of Faculty of Psychiatry, Harvard Medical School
1 Bowdoin Square, 6th Floor
Boston, MA 02114 David Mischoulon, M.D. Ph.D.
Director, Depression Clinical and Research Program, Massachusetts General Hospital
Associate Professor of Psychiatry, Harvard Medical School
1 Bowdoin Square, 6th Floor
Boston, MA 02114

Cristina Cusin, M.D.
Director, Translational Studies in the Depression Clinical and Research Program, Massachusetts General Hospital
Assistant Professor of Psychiatry, Harvard Medical School
1 Bowdoin Square, 6th Floor
Boston, MA 02114

David Mischoulon is an Associate Psychiatrist at Massachusetts General Hospital, an Associate Professor of Psychiatry at Harvard Medical School, and the Director of Research and Alternative Remedy Studies at the Depression Clinical and Research Program at Massachusetts General Hospital. Dr. Mischoulon graduated from the combined MD-PhD program at Boston University School of Medicine in 1994, and then interned in preliminary medicine at Carney Hospital from 1994-1995. From 1995-1998 he completed his residency in adult psychiatry at Massachusetts General Hospital, where he served as Chief Resident in Psychopharmacology. Dr. Mischoulon has authored or co-authored more than 100original articles, review articles, and book chapters, and has also co-edited a textbook on natural medications for psychiatric disorders.

Zusammenfassung

Major Depressive Disorder (MDD) is one of the most prevalent psychiatric disorders, with a lifetime prevalence rate of roughly 20%. MDD is a leading cause of disability and premature death worldwide, leads to greater impairment in work functioning than other chronic medical conditions, and has an estimated annual cost of $210 billion in the US.

The proposed text is designed for mental health professionals and will present state-of-the-art treatment options that are used in the Depression Clinical and Research Program (DCRP) at the Massachusetts General Hospital. The text provides different treatment options so that providers can 'think outside the box' of conventional interventions. The introductory sections discuss general themes about diagnosing and treating depression. The major body of the book, however, consists of chapters organized under the topics of new medication, new psychotherapy, alternative treatments, and consideration of specific populations and how to modify interventions to best treat these patients. Each chapter begins with a case vignette to illustrate key characteristics of the disorder process or treatment and reviews the history, research support, and new advances of these topics. In addition, the chapters include a description of how to apply this topic in treatment and frequently asked questions and answers.

This book will be a unique contribution to the field. Existing guides focus on individual treatments of Depression, or include brief descriptions of interventions as a whole. The DCRP has consistently been a forerunner of clinical treatments for depression and often treats challenging cases of this disorder. This book will provide a practical and useful resource with wide applicability.

Inhalt

Foreword-MGH Guide to Depression

Jerrold Rosenbaum

Foreword-Introduction and Historical Perspective

Maurizio Fava

Preface Benjamin G. Shapero, David Mischoulon, Cristina Cusin

Part 1 Severe and Comorbid Conditions

Chapter 1

Treatment-Resistant Depression Cristina Cusin and Stefan Peyda

Chapter 2

Co-Occurring MDD and Problematic Alcohol Use

Paola Pedrelli and Kate H. Bentley

Part 2 Special Population Considerations

Chapter 3

Depression and Chronic Medical Illness: New Treatment Approaches

Trina E. Chang and Sean D. Boyden

Chapter 4

Culture and Depression: Clinical Considerations for Racial and Ethnic Minorities

Nhi-Ha Trinh and Taquesha Dean

Chapter 5 Early Onset of Depression During Childhood and Adolescence

Benjamin G. Shapero and Erica Mazzone

Chapter 6

Cross-Cultural Approaches to Mental Health Challenges Among Students

Xiaoqiao Zhang, Tat Shing Yeung, Yi Yang, Rohit M. Chandra, Cindy H. Liu, Dana Wang, Sukhmani K. Bal, Yun Zhu, Rebecca Nika W. Tsai, Zhenyu Zhang, Lusha Liu and Justin A. Chen

Chapter 7

Depression After Traumatic Brain Injury

Lauren B. Fisher, Garrett Thomas, Ryan A. Mace, and Ross Zafonte

Part 3 Medication Approaches

Chapter 8

Personalized Medicine

Simmie L. Foster, Samuel R. Petrie, David Mischoulon, and Maurizio Fava

Chapter 9

Depression, Antidepressants, and Sexual Functioning

Christina M. Dording and Sean D. Boyden

Chapter 10 Ketamine as a Rapid Antidepressant

Cristina Cusin

Chapter 11

Neuroactive Steroids and Depression

Karen K. Miller

Part 4 Psychotherapy Approaches

Chapter 12

Unified Protocol for Treatment of Depression

Kate H. Bentley, Laren R. Conklin, James F. Boswell, Benjamin G. Shapero, and Olenka S. Olesnycky

Chapter 13

Mindfulness Based Cognitive Therapy

Benjamin G. Shapero, Jonathan Greenberg, Paola Pedrelli, Gaelle Desbordes, and Sara W. Lazar

Chapter 14

The Role of Technology in the Treatment of Depression

Paola Pedrelli, Kate H. Bentley, Esther Howe, and Benjamin G. Shapero

Part 5 Alternative Treatment Approaches

Chapter 15

Supplements and Natural Remedies for Depression

David Mischoulon and Nadia Iovieno

Chapter 16 The Effects of Tai Chi and Qigong on Anxiety and Depression

Albert Yeung, Benjamin Campbell, and Jessie S. M. Chan

Chapter 17

Yoga as a Treatment for Depression

Maren Nyer, Regina Roberg, Maya Nauphal, and Chris Streeter

Chapter 18

Photobiomodulation Marco Antonio Caldieraro and Paolo Cassano