Clinical trials with Lipiodol l3ll were started in 1961 by my associate, S. CHIAPPA, and a group of physicians at the Institute of Radiology and the National Cancer Institute in Milan and development has been vigorously pursued during the past years. Once the rationale of this method was established, various aspects of the prob lem have been investigated, particularly the distribution of the radioactive dye into the lymph nodes as weIl as its fate and dosimetry in the body tissues. This mono graph describes the extensive clinical evaluation and the radiological results obtained in a large group of patients with malignant lymphomas. Endolymphatic radiotherapy as a therapeutic tool employing radiönuclides has aroused interest at several meetings concerned with lymphology. In the re cent mono graph "Lymphography in cancer" by W. A. FUCHS, J. W. DAVIDSON and H. W. FISCHER, Dr. JANTET wrote a chapter on this specific subject. Many aspects are still debated, i. e. the choice of radionuclide, the specific clinical indications and the proper evaluation of the therapeutic effects. It is hoped that further studies will come to more precise conclusions.

Inhalt

1 Present Position of Radical and Palliative Treatment of Malignant Lymphomas.- 2 Lymphangiography and Endolymphatic Radiotherapy: General Principles.- 3 Technique of Lymphography and Endolymphatic Radiotherapy.- 4 Physical Properties of Lipiodol 131I and Dosimetric Studies.- 5 Clinical Results of Endolymphatic Radiotherapy.- 6 Side Effects and Complications.- 7 Results of Endolymphatic Radiotherapy: Histological Aspects..- 8 Endolymphatic Radiotherapy in Relation to Other Treatments for Malignant Lymphomas.- 9 Conclusions..