Recent developments with respect to the biology and clinical use of retinoids in cancer therapy and prevention are comprehensively covered by experts in this new field. Newer aspects of molecular mechanisms of retinoid effects, the cellular biology and the developmental effects of these compounds are presented together with a comprehensive description of the latest findings of retinoid pharmacology, toxicology and clinical effects in a wide range of hematological and solid malignancies.

Inhalt

Molecular Mechanisms of Retinoid Action.- Cellular Biology of the Retinoids.- Retinoids and Embryos.- Clinical Pharmacology of the Retinoids.- Clinical Toxicology of the Retinoids.- Clinical and Molecular Advances in Acute Promyelocytic Leukaemia.- Retinoid Therapy of Other Haematological Malignancies.- Retinoids in the Prevention and Therapy of Solid Tumours.- Retinoids in Oncology: Conclusions and Future Directions.