Process Scale Liquid Chromatography

Ein Buch über die Flüssigkeitschromatographie im industriellen Maßstab für Chemiker und Ingenieure in der Produktion. Es bietet einen verständlichen Überblick und vermittelt grundlegende Theorien. Darüber hinaus wird dem Leser gezeigt, wie wichtig die Auslegung der Systeme sowie Simulationen und Modelle sind. Dabei werden auch wirtschaftliche Gesichtspunkte berücksichtigt. Einen weiteren Schwerpunkt bilden Sicherheitsfragen und
Regulierungsfaktoren.

Der aktuelle Überblick über die gängigen Techniken und Medien der Flüssigkeitschromatographie zeigt deren Vorteile und Grenzen und ermöglicht ihre praktische Anwendung bei den täglich auftretenden Problemen.

Die Beiträge sind von anerkannten europäischen und amerikanischen Spezialisten verfaßt und machen dieses Buch zur Fundgrube für den Anwender der Flüssigkeitschromatographie in der Industrie.

Autorentext

Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years of experience in industry and academia, encompassing the application and development of processing, purification methodologies, and chromatographic systems for large scale use in environmental science, food science, perfumery, cosmetics, and pharmaceuticals. He has also taught extensively in the area of food and medical technology. A chemistry graduate from Madras, India, Dr. Subramanian was awarded his doctorate from the University of Glasgow for work on natural products. His main research interests lie in the utilization of natural material separation processes and bioconversions. Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. He also organizes conferences promoting the integration and sharing of knowledge between academia and industry.

Zusammenfassung
This book provides the industrial chromatographer and production scientist with a comprehensive account of process scale liquid chromatography. The basic theory is presented, guiding the reader through system design, simulation and modelling techniques, giving due consideration to economic aspects, as well as safety and regulatory factors.

A thorough, up-to-date survey of current techniques and media does stress their advantages and limitations in such a way as to faciliate their application to real-life problems. In view of rapid rate of development in industrial chromatography one chapter provides an assessment of future developments.

The chapters are written by acknowledged experts from Europe and the United States.

Inhalt
Chromatography systems, Design and Control (F. Mann)
The Practical Application of Theory in Preparative Liquid Chromatography (G. B. Cox)
Alternative Modes of Operation of Chromatography Columns in the Process Situation (D. A. Hill)
Process Scale Size Exclusion Chromatography (J.-C. Janson)
Polymers and their Application in Liquid Chromatography (L. L. Lloyd /
J. F. Kennedy)
Biochemical Applications of Process-Scale Ion-Exchange Liquid Chromatography (P. R. Levison)
Instrumental Design and Separation in Large-Scale Industrial Supercritical Fluid Chromatography (P. Jusforgues)
Scaling-up of Supercritical Fluid Chromatography to Large-Scale Separation (C. D. Bevan /
C. J. Mellish)
Affinity Chromatography and its Applications in Large-Scale Separations. (C. R. Goward)